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Table 1 Different patterns of fatal asthma

From: Clinical review: Severe asthma

 

Scenario of asthma death

Variable

Type 1

Type 2

Time course

Subacute worsening (days). 'Slow onset – late arrival'

Acute deterioration (hours). 'Sudden asphyxic asthma'

Frequency

≅ 80–85%

≅ 15–20%

Airways

Extensive mucous plugging

More or less 'empty' bronchi

Inflammation

Eosinophils

Neutrophils

Response to treatment

Slow

Faster

Prevention

Possible

(?)