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Table 1 Demographic and clinical details of the sample at the time of the intervention a

From: Early mobilization on continuous renal replacement therapy is safe and may improve filter life

Variable Baseline group (n = 19) Intervention group (n = 33) Femoral (n = 23) Nonfemoral (n = 10)
Age, yr 63.6 (13.6) 63.7 (14.8) 63.7 (14.1) 63.6 (17.2)
Sex, % male 79% 61% 65% 50%
BMI 28.0 (5.1) 29.3 (10.6) 31.7 (11.2) 23.9 (7.0)
Diagnosis, %     
  Cardiogenic shock/cardiac 26% 33% 30% 40%
  Septic shock/sepsis/MOF 47% 43% 44% 40%
  Renal/metabolic/electrolyte 21% 15% 17% 10%
  Haemorrhagic shock/haematoma 0% 9% 9% 10%
  Vascular surgery 5% 0% 0% 0%
APACHE II score 26.1 (7.2) 25.7 (6.8) 26.9 (8.2)
APACHE III score 98.3 (26.9) 93.8 (24.9) 91.1 (23.1) 100.0 (29.1)
ICU length of stay, days 10.2 (6.9) 15.0 (10.0) 15.4 (9.3) 14.1 (11.8)
MV, % 74% 76% 74% 80%
  MV hours, median (IQR) 78 (0 to 153) 76 (0 to 267) 89 (0 to 295) 63 (30 to 190)
Siteb, %     
  Femoral 63% 70% 100% 0%
  Internal jugular 37% 21% 0% 70%
  Subclavian 0% 9% 0% 30%
Catheter typec, n (%)     
  Dolphin Protect 13 (68%) 19 (58%) 13 (57%) 6 (55%)
  Niagara™ 5 (26%) 9 (27%) 7 (30%) 2 (18%)
  Arrow-Howes™ 1 (5%) 5 (15%) 3 (13%) 1 (9%)
Intervention filter type, %     
  Prismaflex ST100 N/A 94% 91% 100%
Intervention filter anticoagulation, %     
  Heparin N/A 27% 26% 30%
  Citrate N/A 6% 4% 10%
  Saline N/A 0% 0% 0%
  Regional circuit N/A 52 48% 60%
  Other N/A 3% 4% 0%
  Nil N/A 12% 17% 0%
FBE on intervention filter, median (IQR)     
  Hb, g/dl N/A 89 (85 to 94) 88 (81 to 91) 93 (90 to 103)
  Platelets, 103 U/L N/A 125 (60 to 200) 121 (59 to 174) 179 (60 to 252)
  INR N/A 1.1 (1.1 to 1.4) 1.2 (1.1 to 1.4) 1.1 (1.1 to 1.3)
  aPTT N/A 39 (34 to 52) 40 (34 to 55) 34 (33 to 44)
RASS, median (IQR) N/A -1 (-4 to 0) -2 (-4 to 0) -1 (-1 to 0)
CAM-ICU positive, % N/A 42% 39% 50%
Hospital LOS in days, median (IQR) 23 (9 to 31) 31 (21 to 57) 29 (21 to 57) 37 (15 to 57)
Hospital mortality, % 42% 15% 17% 10%
  1. aaPTT, Activated thromboplastin time; BMI: Body mass index; CAM-ICU: Confusion Assessment Method for the ICU; FBE: Full blood examination; Hb: Haemoglobin; ICU: Intensive care unit; INR: International normalized ratio; IQR: Interquartile range; LOS: Length of stay; MOF: Multiorgan failure; MV: Mechanical ventilation; N/A: Not applicable; RASS: Richmond Agitation–Sedation Scale. bFemoral (14 in right, 9 in left), intrajugular (6 in right, 1 in left) and subclavian (3 in left, 1 in right). cDolphin Protect (13-French gauge, 25 cm; Gambro, Hechingen, Germany), Niagara™ (13.5-French gauge; Bard Access Systems, Salt Lake City, UT, USA), Arrow-Howes™ triple-lumen (13-French, 20 cm; Teleflex, Research Triangle Park, NC, USA). Data are mean (SD) unless otherwise specified. Percentages may not add up to 100% due to rounding.