Table 2 General characteristics of study patients according to sedation depth
Characteristic | All patients (n = 322) | Light sedation (n = 209) | Deep sedation (n = 113) | P valuea |
|---|---|---|---|---|
Age (years) | 59 (40.8 to 74) | 61 (44 to 74.5) | 55 (33.5 to 73) | 0.068 |
Male gender | 187 (58) | 108 (52) | 79 (70) | 0.002 |
Charlson comorbidity index | ||||
0 | 136 (42.2) | 72 (34.4) | 64 (56.7) | <0.001 |
1 to 2 | 107 (33.2) | 75 (35.9) | 32 (28.3) | |
> 2 | 79 (24.5) | 62 (29.7) | 17 (15) | |
Comorbidities | ||||
Hypertension | 121 (37.7) | 88 (42.1) | 33 (29.2) | 0.026 |
Diabetes | 72 (22.4) | 50 (25.4) | 22 (17.6) | 0.381 |
Heart failure | 26 (8.1) | 21 (10.7) | 5 (14.7) | 0.077 |
COPD | 24 (7.5) | 21 (10) | 3 (2.7) | 0.016 |
Chronic renal failure | 34 (10.6) | 24 (12.2) | 10 (8) | 0.463 |
Admission source | 0.103 | |||
Ward | 101 (31.4) | 74 (35.4) | 27 (23.9) | |
Emergency room | 125 (38.8) | 77 (36.8) | 48 (42.5) | |
Operation room | 96 (29.8) | 58 (27.8) | 38 (33.6) | |
Admission scores (points) | ||||
Admission SAPS3 | 61 (50 to 72) | 59 (48 to 70) | 65 (54 to 78) | 0.001 |
SOFA score day 1 | 8 (6 to 11) | 8 (5 to 11) | 9 (7 to 11) | 0.001 |
Cause of respiratory failure | ||||
Pneumonia | 105 (32.6) | 69 (33) | 36 (31.9) | 0.833 |
Nonpulmonary sepsis | 45 (14) | 30 (14.4) | 15 (13.3) | 0.790 |
Asthma/COPD | 30 (9.3) | 19 (9.1) | 11 (9.7) | 0.850 |
Cardiogenic pulmonary edema | 20 (6.2) | 15 (7.2) | 5 (4.4) | 0.329 |
Extracranial trauma | 23 (7.1) | 13 (6.2) | 10 (8.8) | 0.382 |
Hypovolemic/cardiogenic shock | 18 (5.6) | 12 (5.7) | 6 (5.3) | 0.872 |
Aspirative syndromes | 13 (4) | 9 (4.3) | 4 (3.5) | 0.739 |
Pulmonary embolism | 9 (2.8) | 6 (2.9) | 3 (2.7) | 0.911 |
Others | 59 (18.3) | 36 (17.2) | 23 (20.4) | 0.488 |