Endogenous thrombin potential following hemostatic therapy with 4-factor prothrombin complex concentrate: a 7-day observational study of trauma patients

Table 2 ROTEM findings on emergency room admission

	NCT group (n = 23)	FC group (n = 21)	FC-PCC group (n = 17)	P-values
				FC-PCC versus NCT	FC-PCC versus FC
EXTEM
CT, sec	58.2 ± 9.5	70.2 ± 21.6	72.6 ± 31.5	0.045	ns
CFT, sec	102.3 ± 29.9	116.0 (96.5 to 160.0)	123.0 (109.0 to 165.0)	0.001	ns
CA10, mm	55.2 ± 6.7	48.1 ± 7.8	46.3 ± 9.2	0.001	ns
FIBTEM
CA10, mm	12.0 (10.0 to 15.0)	8.0 (7.0 to 12.5)	8.0 (4.3 to 11.8)	0.0094	ns

CA10, clot amplitude after 10 minutes running time; CT, clotting time; CFT, clot formation time; EXTEM, extrinsically activated test; FIBTEM, extrinsically activated test plus cytochalasin D; NCT group, no coagulation therapy; FC group, fibrinogen concentrate only; FC-PCC group, prothrombin complex concentrate and fibrinogen concentrate. Data are presented as mean ± standard deviation or median (interquartile range).
P-values are derived from t-test or Mann-Whitney U-test; significance level P <0.05; ns, not significant.

ISSN: 1364-8535