Relationship between change in endogenous thrombin potential and change in antithrombin, from emergency room (ER) admission until day 7 following trauma. In the FC-PCC group, a pronounced gap between endogenous thrombin potential and antithrombin was observed. ETP, endogenous thrombin potential (solid symbols); AT, antithrombin (open symbols); NCT group (triangles), patients who received no coagulation therapy; FC group (squares), patients who received fibrinogen concentrate only; FC-PCC group (circles), patients who were treated with prothrombin complex concentrate and human fibrinogen concentrate. *P <0.05; ***P <0.001; not indicated = not significant (within-group comparison versus ER admission). Data are presented as median (interquartile range).