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Figure 1 | Critical Care

Figure 1

From: Prolonged continuous intravenous infusion of the dipeptide L-alanine- L-glutamine significantly increases plasma glutamine and alanine without elevating brain glutamate in patients with severe traumatic brain injury

Figure 1

Study protocol investigating the effects of continuously infusing L-alanine-L- glutamine (Dipeptiven® = L-alanine-L-glutamine; 82 mg L-alanine, 134.6 mg L-glutamine; 0.5 g glutamine/kg) for 24 hours (study 1) or 5 days (study 2) in six patients each suffering from severe traumatic brain injury. The representative computed tomography (CT) scan shows the position of the microdialysis catheter and intracranial pressure probe. ICP, intracranial pressure; CPP, cerebral perfusion pressure; ptiO2, brain tissue oxygen; SjvO2, jugular venous oxygen saturation; BIS EEG, bispectral index electroencephalogram.

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