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Table 2 Comparison of biochemical measures and urine output after the randomized treatment period of approximately 120 h

From: Continuous versus bolus intermittent loop diuretic infusion in acutely decompensated heart failure: a prospective randomized trial

 

Continuous infusion

Bolus

P-value

Urine output/24 h (mL)

2295 ± 775

2090 ± 421

<0.002

Serum creatinine (mg/dl)

1.78 ± 0.6

1.34 ± 0.3

<0.0001

eGFR (mL/min/1.73 m2)

40.6 ± 10.5

50.4 ± 11.4

<0.01

BUN (mg/dl)

100 ± 60

69 ± 31

<0.02

BNP (pg/mL)

723 ± 497

822 ± 548

<0.05

Serum sodium (mEq/L)

138 ± 4

135 ± 16

NS

Serum potassium (mEq/L)

3.6 ± 0.8

4.0 ± 0.7

<0.04

  1. Results are presented as mean ± SD. eGFR, estimated glomerular filtration rate; BUN, blood urea nitrogen; BNP, B-type natriuretic peptide; NS, not significant.