Characteristics | Controls | Cases | P value |
---|---|---|---|
(n = 328) | (n = 328) | ||
Demographics | Â | Â | Â |
Age, median (IQR) | 64 (49-78) | 67 (55-79) | 0.01 |
Body mass index, median (IQR) | 28 (23-32) | 27 (23-31) | 0.3 |
Female, n (%) | 207 (63) | 173 (53) | 0.01 |
Race, n (%) | Â | Â | 0.02 |
White, non-Hispanic | 60 (18) | 93 (28) | Â |
Black, non-Hispanic | 111 (34) | 96 (29) | Â |
Hispanic | 134 (41) | 109 (33) | Â |
Other | 23 (7) | 30 (9) | Â |
Service, n (%) | Â | Â | 0.2 |
Medical | 269 (82) | 255 (78) | Â |
Surgical | 59 (18) | 73 (22) | Â |
Suspected source of infection, n (%) | Â | Â | |
Pneumonia | 84 (26) | 135 (42) | <0.001 |
Urinary tract | 92 (28) | 73 (22) | 0.09 |
Skin or soft tissue | 20 (6) | 14 (4) | 0.3 |
Peritonitis | 3 (1) | 9 (3) | 0.14 |
Other | 134 (41) | 119 (36) | 0.3 |
Comorbidities, n (%) | Â | Â | Â |
Severe sepsis | 106 (32) | 248 (76) | <0.001 |
Chronic liver disease | 77 (23) | 83 (25) | 0.6 |
Chronic pulmonary disease | 136 (41) | 123 (38) | 0.3 |
Chronic renal disease | 82 (25) | 89 (27) | 0.6 |
Congestive heart failure | 97 (30) | 125 (38) | 0.02 |
Diabetes mellitus | 122 (41) | 127 (43) | 0.7 |
History of myocardial infarction | 49 (15) | 57 (17) | 0.5 |
Human immunodeficiency virus | 21 (6) | 15 (5) | 0.4 |
Malignancy | 61 (19) | 76 (23) | 0.17 |
Metastatic | 23 (7) | 29 (9) | 0.5 |