Nitroglycerin reverts clinical manifestations of poor peripheral perfusion in patients with circulatory shock

Table 2 Global hemodynamic variables recorded in the three different time points during execution of the study protocol (n = 15)

	T_BL1	T_MX	T_BL2
Heart rate, beats per minute	95 (4.3)	97 (4.4)	98 (4.4)
Systolic blood pressure, mm Hg	113 (4.6)	94 (4.0)^a	111 (3.8)^a
Diastolic blood pressure, mm Hg	52 (4.9)	49 (4.8)^a	57 (4.9)^a
Mean arterial blood pressure, mm Hg	75 (3.0)	61 (2.9)^a	71 (2.3)^a
Central venous pressure, mm Hg	12 (4.0)	9 (5.0)^a	10 (6.0)
Cardiac index, n = 6, L/min per m²	4.1 (0.4)	3.8 (0.5)	3.9 (0.4)
Stroke volume, n = 6, mL	78 (15)	66 (14)	77 (12)

Data are presented as mean (standard error). ^aP <0.05 versus previous time point (linear model for repeated measurements). Time points are defined as before nitroglycerin infusion (T_BL1), at the maximum dose of nitroglycerin (T_MX), and 30 minutes after cessation of nitroglycerin (T_BL2). Cardiac index and stroke volume were measured in six patients.

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