Standard operating procedures for antibiotic therapy and the occurrence of acute kidney injury: a prospective, clinical, non-interventional, observational study

Table 3 Multivariate regression analysis including covariates significantly associated with development of AKI in univariate analyses

	Odds ratio (95% CI)	P-value
Age	0.984 (0.972, 1.017)	0.607
SOFA (on admission)	1.063 (0.981, 1.151)	0.137
Chronic kidney failure	2.346 (1.061, 5.189)	0.035
Operation before admission	0.907 (0.420, 1.962)	0.805
Septic shock	1.105 (0.472, 2.587)	0.818
Immune suppression	1.621 (0.638, 4.118)	0.310
Adherence to SOP (LAG versus HAG)	2.054 (0.986, 4.280)	0.055

Significant covariates were included in multivariate regression analysis (Hosmer-Lemeshow test, χ 2 = 10.312; P = 0.244). SOFA, sequential organ failure assessment; SOP, standard operating procedure; HAG, high-adherence group; LAG, low-adherence group

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