Survivors (n = 76) | Deaths (n = 41) | P value | |
---|---|---|---|
Demographic variables | |||
Gender (female) | 39 (51.3) | 13 (31.7) | 0.042 |
Age | 63 (52 to 73) | 66 (52 to 74) | 0.301 |
Underlying diseases | |||
Diabetes | 14 (18.4) | 9 (22) | 0.647 |
Cirrhosis | 1 (1.3) | 4 (9.8) | 0.050 |
ESRD | 6 (7.9) | 4 (9.8) | 0.739 |
Immunosuppression | 10 (13.2) | 6 (14.6) | 0.825 |
Cancer | 4 (5.3) | 11 (26.8) | 0.001 |
Chronic cardiac insufficiency | 5 (6.6) | 2 (4.9) | 0.998 |
COPD | 9 (11.8) | 7 (17.1) | 0.432 |
SIRS | |||
Two SIRS criteria | 21 (27.6) | 8 (19.5) | 0.027 |
Three SIRS criteria | 28 (36.8) | 8 (19.5) | |
Four SIRS criteria | 27 (35.5) | 25 (61) | |
Severity scores | |||
APACHE II | 16 (12 to 22) | 22 (16 to 27) | 0.001 |
SOFA | 7 (4 to 11) | 10 (6 to 13) | 0.007 |
Laboratory parametersa | |||
Leukocytes day 1 | 13,035 (9,565) | 14,340 (12,730) | 0.591 |
Leukocytes day 2 | 14,345 (8,208) | 17,780 (12,665) | 0.010 |
Eosinophils day 1 | 50.13 (11.80) | 83.41 (35.83) | 0.055 |
Eosinophils day 2 | 82.23 (14.65) | 123.24 (52.62) | 0.747 |
CRP day 1 | 30.41 (15.77) | 23.32 (20.91) | 0.101 |
CRP day 2 | 29.84 (18.36) | 30.72 (20.11) | 0.794 |
PCT day 1 | 13.50 (45.26) | 15.07 (57.42) | |
PCT day 2 | 8.34 (22.55) | 12.13 (40.47) | |
cf-DNA day 1 | 5,490 (5,080) | 6,660 (7,745) | 0.495 |
cf-DNA day 2 | 4,830 (6,135) | 5,460 (5,400) | 0.890 |
Source of infection | |||
Surgical | 40 (52.6) | 29 (70.7) | 0.058 |
Nosocomial | 28 (36.8) | 16 (39) | 0.816 |
Respiratory | 17 (22.4) | 8 (19.5) | 0.719 |
Urinary | 12 (15.8) | 2 (4.9) | 0.134 |
Abdominal | 35 (46.1) | 18 (43.9) | 0.824 |
Central nervous system | 1 (1.3) | 0 | 0.999 |
Soft tissues | 5 (6.6) | 4 (9.8) | 0.718 |
Bacteriemic | 22 (28.9) | 14 (31.4) | 0.561 |
Unknown | 3 (3.9) | 2 (4.9) | 0.999 |
Others | 3 (3.9) | 7 (17.1) | 0.032 |
Outcomes | |||
Length of stay in ICU | 8 (4 to 18) | 6 (3 to 14) | 0.089 |
Length of stay in hospital | 26 (18 to 43) | 12 (5 to 22) | <0.001 |