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Figure 3 | Critical Care

Figure 3

From: The effect of prone positioning on mortality in patients with acute respiratory distress syndrome: a meta-analysis of randomized controlled trials

Figure 3

Meta-analysis of the effect of prone positioning on 28- to 30-day mortality related to positive end-expiratory pressure in acute respiratory distress syndrome patients. The evidence we gathered shows obvious heterogeneity, which we calculated using the Mantel–Haenszel (M-H) χ2 test (P = 0.01) and an I2 test (I2 = 64%). A random-effects model was used. The z-test result for overall effects was not statistically significant (P = 0.18). In the subgroup of patients with positive end-expiratory pressure (PEEP) < 10 cmH2O, the z-test result for overall effects was not statistically significant (P = 0.61). In the subgroup of patients with PEEP values between 10 and 13 cmH2O, the z-test result for overall effects was statistically significant (P = 0.09). “Weight” is the contribution of each study to the overall risk ratio. CI, Confidence interval; I2, percentage of total variation across studies from between-study heterogeneity rather than chance; PP, Prone positioning; SP, Supine positioning.

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