Table 1 Characteristics of the patients a
From: Circulating cytokines in predicting development of severe acute pancreatitis
Characteristics | All patients (N= 163) | Mild or moderately severe AP (n= 138) | P- valueb | Severe AP (n= 25) | |||
|---|---|---|---|---|---|---|---|
All (N= 25) | MMS <2 (n= 14) | P- value | MMS ≥2 (n= 11) | ||||
Men | 120 (73.6) | 96 (69.6) | 0.006 | 24 (96.0) | 13 (92.9) | NS | 11 (100.0) |
Age, years | 48 (18 to 87) | 49 (18 to 87) | NS | 43 (29 to 81) | 41 (29 to 81) | NS | 51 (29 to 69) |
Etiology | |||||||
Alcohol | 113 (69.3) | 91 (65.9) | 0.028 | 22 (88.0) | 11 (78.6) | NS | 11 (100) |
Biliary | 35 (21.5) | 34 (24.6) | 0.021 | 1 (4.0) | 1 (7.1) | NS | 0 |
Other cause | 11 (6.7) | 9 (6.5) | NS | 2 (8.0) | 2 (14.3) | NS | 0 |
Idiopathic | 4 (2.5) | 4 (2.9) | NS | 0 | 0 | NS | 0 |
Onset of symptoms, hr | 24 (1 to 72) | 24 (1 to 72) | NS | 24 (3 to 72) | 18 (3 to 48) | <0.001 | 48 (24 to 72) |
C-reactive protein, mg/L | 19 (3 to 435) | 16 (3 to 426) | 0.002 | 94 (3 to 435) | 30 (3 to 229) | <0.001 | 294 (22 to 435) |
Creatinine, μmol/L | 64 (31 to 1086) | 62 (31 to 313) | <0.001 | 92 (47 to 1086) | 68 (47 to 147) | <0.001 | 248 (92 to 1086) |
Calcium, mmol/L | 2.2 (1.27 to 2.73) | 2.23 (1.27 to 2.73) | <0.001 | 1.86 (1.39 to 2.30) | 2.04 (1.49 to 2.30) | 0.013 | 1.67 (1.39 to 2.17) |
Length of hospital stay, days | 6 (1 to 93) | 5 (1 to 41) | <0.001 | 26 (1 to 93) | 28 (1 to 93) | NS | 17 (1 to 49) |
Mechanical ventilation | 25 (15.3) | 2 (1.4) | <0.001 | 23 (92.0) | 13 (92.9) | NS | 10 (90.9) |
Renal replacement therapy | 16 (9.8) | 0 | <0.001 | 16 (64.0) | 7 (50.0) | NS | 9 (81.8) |
OD within 24 hours | 30 (18.4) | 10 (7.2) | <0.001 | 20 (80.0) | 9 (64.3) | NS | 11 (100) |
OD on days 1 to 7 | 5 (3.1) | 0 | <0.001 | 5 (20.0) | 5 (37.5) | NS | 0 (0) |
Mortality | 8 (4.9) | 1 (0.7) | 0.014 | 7 (28.0) | 2 (14.3) | NS | 5 (45.5) |