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Table 4 Effects of high-frequency oscillatory ventilation on physiological outcomes in patients with acute respiratory distress syndrome

From: Efficacy and adverse events of high-frequency oscillatory ventilation in adult patients with acute respiratory distress syndrome: a meta-analysis

Outcome

Number of studies (patients)

Ratio of means (95% CI); P value

P value for heterogeneity; I2

PaO2/FIO2

   

  Day 1

4 (1032)

1.24 (1.11-1.40); <0.001

0.119; 49%

  Day 2

4 (1032)

1.13 (0.94-1.37); 0.2

0.002; 79%

  Day 3

4 (1032)

1.16 (0.99-1.35); 0.072

0.012; 73%

Mean airway pressure, cmH2O

   

  Day 1

4 (785)

1.31 (1.25-1.36); <0.001

0.001; 81%

  Day 2

3 (237)

1.28 (1.18-1.38); <0.001

0.002; 84%

  Day 3

4 (785)

1.25 (1.15-1.36); <0.001

<0.001; 90%

PaCO2, mmH2O

   

  Day 1

5 (1580)

0.97 (0.87-1.07); 0.494

<0.001; 94%

  Day 2

4 (1032)

0.96 (0.83-1.11); 0.554

<0.001; 97%

  Day 3

5 (1580)

1.11 (0.99-1.23); 0.068

<0.001; 96%

  1. CI, confidence interval; PaO2, partial pressure of oxygen in arterial blood; FIO2, fraction of inspired oxygen; PaCO2, partial pressure of carbon dioxide in arterial blood.