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Table 2 Ventilator settings in included studies

From: Efficacy and adverse events of high-frequency oscillatory ventilation in adult patients with acute respiratory distress syndrome: a meta-analysis

 

Derdak et al. 2002[12]

Shah et al. 2004[13]

Bollen et al. 2005[14]

Ferguson et al. 2013[18]

Young et al. 2013[17]

HFOV

     

  Mean airway pressure

5 cmH2O above mean airway pressure on CMV

5 cmH2O above mean airway pressure on CMV

5 cmH2O above mean airway pressure on CMV

30 cmH2O

5 cmH2O above plateau pressure on CMV

  Frequency, Hz

5

5

5

3-12

10

  Amplitude

To achieve chest wall vibration to the level of the midthigh

To achieve chest wall to midthigh vibration

According to PaCO2 and to achieve chest wall vibration

90 cmH2O

A cycle volume of 100 ml

CMV

     

  Mode

Pressure control ventilation

Pressure control ventilation

Pressure control ventilation

Pressure control ventilation

Pressure control ventilation

  Tidal volume

6-10 ml/kg (actual body weight)

A mean of 7-8 ml/kg (ideal body weight)

A mean of 8-9 ml/kg (ideal body weight)

6 ml/kg (predicted body weight)

6-8 ml/kg (ideal body weight)

  Adjustment of PEEP

Study protocol

ARDS Network protocol

Not reported

Lung Open Ventilation Study

ARDS Network protocol

  1. HFOV, high-frequency oscillatory ventilation; CMV, conventional mechanical ventilation; PaCO2, partial pressure of carbon dioxide in arterial blood; PEEP, positive end-expiratory pressure; ARDS, acute respiratory distress syndrome.