Table 1 Demography, clinical presentation, biomarkers, and infarction characteristics of patients with acute myocardial infarction

Demography

Age (years)

59 ± 13

66 ± 14

59 ± 13

0.067

Male gender

118 (89.4%)

12 (92.3%)

106 (89.1%)

1.000

Hypertension

64 (48.5%)

11 (84.6%)

53 (44.5%)

0.008

Diabetes

36 (27.3%)

6 (46.2%)

30 (25.2%)

0.107

Hyperlipidemia

33 (25%)

3 (23.1%)

30 (25.2%)

1.000

Current smoker

84 (63.6%)

8 (61.5%)

76 (63.9%)

0.868

CAD history

20 (15.2%)

7 (53.8%)

13 (10.9%)

<0.001

Body mass index (kg/m²)

25.6 ± 3.7

25.7 ± 3.6

25.6 ± 3.7

0.974

Clinical presentation

Door-to-balloon time (minutes)

74 ± 42

73 ± 11

74 ± 44

0.909

Systolic blood pressure (mmHg)

139 ± 39

136 ± 66

140 ± 36

0.852

Diastolic blood pressure (mmHg)

89 ± 25

87 ± 48

89 ± 21

0.883

Heart rate (beats/minute)

77 ± 21

89 ± 41

75 ± 18

0.270

Killip class ≥3

32 (24.2%)

8 (61.5%)

24 (20.2%)

0.001

Killip class

 1

87 (65.9%)

3 (23.1%)

84 (70.6%)

 2

13 (9.8%)

2 (15.4%)

11 (9.2%)

 3

10 (7.6%)

4 (30.8%)

6 (5.0%)

 4

22 (16.7%)

4 (30.8%)

18 (15.1%)

LVEF (%)

55 ± 13

46 ± 21

56 ± 11

0.112

eGFR (ml/minute/1.73 m²)

88.0 ± 28.5

46.5 ± 20.2

92.5 ± 25.5

<0.001

Contrast medium (ml)

249 ± 61

254 ± 33

248 ± 63

0.846

Hematology and biomarkers of myocardial necrosis and inflammation

Leukocyte count (/ml)

11,632 ± 4,569

15,954 ± 8,647

11,160 ± 3,646

<0.001

Hemoglobin (g/dl)

14.7 ± 1.8

14.1 ± 1.9

14.8 ± 1.8

0.195

Platelet count (1,000/ml)

226 ± 67

271 ± 139

222 ± 53

0.222

Peak creatine kinase-MB (units/l)

280 ± 254

327 ± 495

275 ± 219

0.734

hsCRP (mg/l)

15.7 ± 27.4

44.86 ± 63.82

13.14 ± 20.38

0.001

Biomarkers of endothelial injury

VEGF (pg/ml)

258.03 ± 373.74

398.10 ± 346.13

241.92 ± 374.86

0.154

Tie-2 (ng/ml)

17.50 ± 8.89

19.02 ± 6.43

17.33 ± 9.13

0.519

vWF (MU)

716.36 ± 216.37

734.31 ± 273.64

714.40 ± 261.12

0.795

Thrombomodulin (ng/ml)

5.56 ± 2.1

7.6 ± 2.26

5.34 ± 2.0

<0.001

Angiopoietin-1 (pg/ml)

29,082.88 ± 20,898.78

36,070.09 ± 21,123.43

28,319.57 ± 20,821.49

0.228

Angiopoietin-2 (pg/ml)

2,798.71 ± 2,439.26

6,338.28 ± 5,862.77

2,412.03 ± 1,256.58

0.033

Infarction type

Culprit vessel

 LMCA

1 (1.3%)

0

1 (0.9%)

1.000

 LAD

69 (52.3%)

8 (61.5%)

61 (51.3%)

0.481

 LCx

10 (7.6%)

0

10 (8.4%)

0.597

 RCA

52 (39.4%)

5 (38.5%)

47 (39.5%)

0.942

 Grafts

0

0

0

Multivessel disease

63 (47.7%)

8 (51.5%)

55 (46.2%)

0.294

Number of involved vessels

 1

68 (51.5%)

5 (38.5%)

29 (24.4%)

 2

38 (28.8%)

4 (30.8%)

22 (18.5%)

 3

25 (18.9%)

2 (15.4%)

17 (14.3%)

Stenting

 Use of DES

75 (56.8%)

5 (38.5%)

70 (58.8%)

0.159

 Use of BMS

36 (27.3%)

3 (23.1%)

33 (27.7%)

1.000

Medications

Aspirin

127 (96.2%)

12 (92.3%)

115 (96.6%)

0.410

Clopidogrel

129 (97.7%)

11 (84.6%)

118 (99.2%)

0.026

Beta-blocker

120 (90.9%)

10 (76.9%)

110 (92.4%)

0.098

ACEI/ARB

96 (72.7%)

11 (84.6%)

85 (71.4%)

0.513

Statin

122 (92.4%)

11 (84.6%)

111 (93.2%)

0.256