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Figure 2 | Critical Care

Figure 2

From: New insights into the mechanisms involved in B-type natriuretic peptide elevation and its prognostic value in septic patients

Figure 2

Daily B- type natriuretic peptide measurements and 5- day B- type natriuretic peptide kinetics in patients with overall critical sepsis (left) and septic shock (right), divided by 28- day mortality. Bars and vertical lines indicate mean B-type natriuretic peptide (BNP) values and standard deviations (SD), respectively. Significant BNP differences on any study day (P < 0.05) are marked with asterisks. Five-day BNP kinetics are indicated by the corresponding mean regression lines (gray in survivors and black in nonsurvivors). Mean regression lines represent similar mean intercepts, yet significantly steeper mean slopes in survivors than in nonsurvivors, either in overall critical sepsis patients (P = 0.001) or in septic shock patients (P = 0.002). The intercept of the regression line is the BNP value where the regression line crosses the y-axis on theoretical day 0. The slope of the regression line is the rate at which BNP values change day after day.

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