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Table 2 Erythrocyte selenium concentration, GPx1 activity, protein carbonyl and mortality according to Pro198Leu polymorphism genotype

From: Erythrocyte selenium concentration predicts intensive care unit and hospital mortality in patients with septic shock: a prospective observational study

Variables

Pro/Pro (n = 57)

Pro/Leu (n = 40)

Leu/Leu (n = 7)

P value

Erythrocyte Se, (μmol/L)

0.41 ± 0.15

0.42 ± 0.14

0.46 ± 0.12

0.655

Protein carbonyl, (nmol/ml)

13.5 (4.6 - 24.2)

7.5 (4.4 - 25.7)

5.3 (3.1 - 17.5)

0.403

GPx1, (U/g Hb)

28.5 (19.8 - 36.7)

31.1 (27.7 - 41.0)

35.9 (24.7 - 51.5)

0.045

SOFA score

8.8 ± 2.6

10.4 ± 4.3

9.1 ± 1.9

0.067

ICU mortality, number (%)

27 (47)

26 (65)

4 (57)

0.227

Hospital mortality, number (%)

31 (54)

30 (75)

5 (71)

0.105

  1. Data are expressed as the mean ± standard deviation (SD), median (including the lower and upper quartiles) or percentage. GPx1, glutathione peroxidase activity; Se, selenium concentration; SOFA, sequential organ failure assessment; ICU, intensive care unit.