|
• Patient background
| |
|
Age, years, mean ± SD
|
66.5 ± 13.9
|
|
Male:female ratio
|
88:66
|
|
• Perforation site, number of patients (%)
| |
|
Small intestine
|
66 (42.9)
|
|
Colon
|
63 (40.9)
|
|
Stomach
|
8 (5.2)
|
|
Duodenum
|
6 (3.9)
|
|
Rectum
|
7 (4.5)
|
|
Combinations
|
4 (2.6)
|
|
• Severity on admission, mean ± SD
| |
|
SOFA score
|
9.14 ± 3.78
|
|
APACHE-II score
|
24.0 ± 8.62
|
|
MOD score
|
4.77 ± 3.23
|
|
MAP on admission, mmHg
|
66.2 ± 29.9
|
|
Blood lactate concentration on admission, mmol/L
|
5.69 ± 4.03
|
|
ScvO2 on admission, %
|
58.9 ± 12.4
|
|
• Extent of peritonitis, number of patients (%)
| |
|
Abscess
|
0 (0)
|
|
One quadrant
|
0 (0)
|
|
Two quadrants
|
9 (5.8)
|
|
Three quadrants
|
76 (49.4)
|
|
Four quadrants
|
71 (44.8)
|
|
• Fluid resuscitation, mean ± SD
| |
|
Infusion volume within 2 hours of admission, ml
|
2858.8 ± 587.5
|
|
Infusion volume within 6 hours of admission, ml
|
5125.2 ± 712.1
|
|
• Microbiology, number of patients (%)
| |
|
Escherichia coli
|
75 (48.7)
|
|
Proteus spp.
|
20 (13.0)
|
|
Klebsiella spp.
|
16 (10.4)
|
|
Pseudomonas aeruginosa
|
20 (13.0)
|
|
Methicillin-resistant Staphylococcus aureus (MRSA)
|
11 (7.1)
|
|
Enterococcus spp.
|
8 (5.2)
|
|
Bacteroides spp.
|
42 (27.3)
|
|
Clostridium spp.
|
6 (4.0)
|
|
Yeast/fungi
|
11 (7.1)
|
|
• Antimicrobial therapy
| |
|
Initial antimicrobial therapy, appropriate:inappropriate ratio
|
124:30
|
|
Time from admission to initiation of antimicrobial therapy, hours*, mean ± SD
|
2.3 ± 0.3
|
|
• Surgery
| |
|
Time from admission to initiation of surgery, hours, mean ± SD
|
3.1 ± 1.5
|
|
Duration of surgery, hours, mean ± SD
|
3.4 ± 1.4
|
|
Addition of re-laparotomy**, number of patients (%)
|
18 (11.7)
|
|
Damage control laparotomy, number of patients (%)
|
0 (0)
|
|
Open abdominal technique, number of patients (%)
|
2 (1.3)
|
|
• ICU stay, days, mean ± SD
|
34.7 ± 36.9
|
|
• Surviving patients, number (%)
| |
|
28-day
|
127 (82.5)
|
|
60-day
|
120 (77.9)
|
