Table 2 Baseline characteristics of all patients
Number of patients: 154 | |
|---|---|
• Patient background | |
Age, years, mean ± SD | 66.5 ± 13.9 |
Male:female ratio | 88:66 |
• Perforation site, number of patients (%) | |
Small intestine | 66 (42.9) |
Colon | 63 (40.9) |
Stomach | 8 (5.2) |
Duodenum | 6 (3.9) |
Rectum | 7 (4.5) |
Combinations | 4 (2.6) |
• Severity on admission, mean ± SD | |
SOFA score | 9.14 ± 3.78 |
APACHE-II score | 24.0 ± 8.62 |
MOD score | 4.77 ± 3.23 |
MAP on admission, mmHg | 66.2 ± 29.9 |
Blood lactate concentration on admission, mmol/L | 5.69 ± 4.03 |
ScvO2 on admission, % | 58.9 ± 12.4 |
• Extent of peritonitis, number of patients (%) | |
Abscess | 0 (0) |
One quadrant | 0 (0) |
Two quadrants | 9 (5.8) |
Three quadrants | 76 (49.4) |
Four quadrants | 71 (44.8) |
• Fluid resuscitation, mean ± SD | |
Infusion volume within 2 hours of admission, ml | 2858.8 ± 587.5 |
Infusion volume within 6 hours of admission, ml | 5125.2 ± 712.1 |
• Microbiology, number of patients (%) | |
Escherichia coli | 75 (48.7) |
Proteus spp. | 20 (13.0) |
Klebsiella spp. | 16 (10.4) |
Pseudomonas aeruginosa | 20 (13.0) |
Methicillin-resistant Staphylococcus aureus (MRSA) | 11 (7.1) |
Enterococcus spp. | 8 (5.2) |
Bacteroides spp. | 42 (27.3) |
Clostridium spp. | 6 (4.0) |
Yeast/fungi | 11 (7.1) |
• Antimicrobial therapy | |
Initial antimicrobial therapy, appropriate:inappropriate ratio | 124:30 |
Time from admission to initiation of antimicrobial therapy, hours*, mean ± SD | 2.3 ± 0.3 |
• Surgery | |
Time from admission to initiation of surgery, hours, mean ± SD | 3.1 ± 1.5 |
Duration of surgery, hours, mean ± SD | 3.4 ± 1.4 |
Addition of re-laparotomy**, number of patients (%) | 18 (11.7) |
Damage control laparotomy, number of patients (%) | 0 (0) |
Open abdominal technique, number of patients (%) | 2 (1.3) |
• ICU stay, days, mean ± SD | 34.7 ± 36.9 |
• Surviving patients, number (%) | |
28-day | 127 (82.5) |
60-day | 120 (77.9) |