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Table 3 Baseline characteristics and suspected VAP episode description of the study patients according to the 30-day mortality

From: Impact of prior statin therapy on the outcome of patients with suspected ventilator-associated pneumonia: an observational study

  Survivors Nonsurvivors P
(n = 249) (n = 100)
Age (years) 62.0 (17.0-94.0) 68.5 (32.0-90.0) <0.01
SAPS II (points) 47.0 (6.0-109.0) 55.0 (15.0-99.0) <0.01
Gender, male (n (%)) 182 (73.1) 72 (72.0) 0.83
Underlying disease(s) (n (%))    
 Chronic renal failure 12 (4.8) 11 (11.0) 0.04
 Cardiac chronic disease 84 (33.9) 54 (54.0) <0.01
 Diabetes mellitus 45 (18.1) 22 (22.0) 0.41
 COPD 45 (18.1) 21 (21.0) 0.53
 Cirrhosis 6 (2.4) 11 (11.0) <0.01
 Immunosuppression 9 (3.6) 8 (8.0) 0.09
 Cancer 25 (10.1) 6 (6.0) 0.21
Nursing-home resident (n (%)) 16 (6.4) 0 (0.0) <0.01
Main admission diagnosis    0.02
 Respiratory distress (n (%)) 101 (40.6) 32 (32.0) 0.13
 Extrapulmonary sepsis (n (%)) 64 (25.7) 43 (43.0) <0.01
 Neurologic failure (n (%)) 40 (16.1) 10 (10.0) 0.14
 Abdominal surgery (n (%)) 14 (5.6) 3 (3.0) 0.30
 Miscellaneous (n (%)) 30 (12.0) 12 (12.0) 0.99
CPIS day 1 6.0 (2.0-11.0) 5.0 (3.0-9.0) 0.06
CPIS day 3 7.0 (5.0-13.0) 7.0 (5.0-11.0) 0.20
SOFA day 1 7.0 (4.0-17.0) 10.0 (4.0-16.0) <0.01
SOFA day 3 7.0 (4.0-16.0) 9.0 (4.0-18.0) <0.01
Length of ICU stay until VAP (days) 10.0 (2.0-157.0) 11.0 (2.0-72.0) 0.48
Duration of MV until VAP (days) 10.0 (2.0-156.0) 10.0 (2.0-70.0) 0.37
Septic shock (VAP day 1) (n (%)) 71 (28.6) 46 (46.0) <0.01
Late-onset VAP (≥5 days after MV onset) (n (%)) 166 (66.7) 75 (75.0) 0.13
MDR bacteria (n (%)) 76 (30.8) 41 (41.0) 0.05
Appropriate antibiotic therapy within the first 24 hours of VAP (n (%)) 193 (78.4) 69 (69.0) 0.16
Steroids during VAP period (n (%)) 89 (36.8) 64 (64.0) <0.01
Statin exposure prior to ICU admission (n (%)) 60 (24.1) 33 (33.0) 0.09
Statin continuation after ICU admission (n (%)) 37 (14.8) 15 (15.0) 0.97
  1. VAP, ventilator-associated pneumonia; SAPS II, simplified acute physiology score II; COPD, chronic obstructive pulmonary disease; CPIS, clinical pulmonary infection score; SOFA, sequential organ failure assessment; ICU, intensive care unit; MV, mechanical ventilation; MDR, multidrug resistant.