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Table 1 Comparisons of clinical variables between cases and controls

From: Comparison of outcomes from sepsis between patients with and without pre-existing left ventricular dysfunction: a case-control analysis

Variable

Cases (n)

Controls (n)

P

Age (years)

68 +/- 16 (197)

67 +/- 16 (197)

0.935b

Male gender

129 (197)

129 (197)

1.000a

LVEF (%)

35 +/- 12 (197)

60 +/- 5 (197)

<0.001 b

APACHE II

20 +/- 7 (194)

19 +/- 8 (191)

0.603b

Initial CVP (cm H2O)

9 +/- 8 (128)

8 +/- 7 (120)

0.334b

ScVO2 (%)

67 +/- 17 (166)

71 +/- 16 (166)

0.009 b

Lung Infection

64 (197)

54 (197)

0.322a

Sepsis bundle compliant

61 (197)

69 (197)

0.453a

MAP <65 mm Hg

116 (197)

114 (197)

0.919a

Initial temperature (°C)

36.9 +/- 1.6 (196)

37.0 +/- 1.5 (195)

0.714b

Temperature at 24 hours (°C)

37.2 +/- 2.0 (197)

37.3 +/- 2.0 (197)

0.471b

Initial heart rate (min−1)

104 +/- 27 (197)

108 +/- 24 (197)

0.074b

Heart rate at 24 hours (min−1)

115 +/- 32 (197)

117 +/- 29 (197)

0.360b

Initial respiratory rate (min−1)

24 +/- 9 (197)

24 +/- 9 (197)

0.558b

Respiratory rate at 24 hours (min−1)

29 +/- 9 (197)

30 +/- 9 (197)

0.435b

Initial MAP (mm Hg)

74 +/- 22 (197)

76 +/- 23 (197)

0.502b

MAP at 24 hours (mm Hg)

58 +/- 19 (197)

60 +/- 21 (197)

0.226b

Initial pH

7.35 +/- 0.12 (176)

7.35 +/- 0.13 (175)

0.994b

pH at 24 hours

7.31 +/- 0.13 (112)

7.29 +/- 0.15 (107)

0.302b

Initial PO2/FiO2

259 +/- 130 (161)

266 +/- 139 (166)

0.630b

PO2/FiO2 at 24 hours

265 +/- 113 (108)

268 +/- 126 (115)

0.846b

Initial sodium (mg/dL)

139 +/- 7 (196)

139 +/- 12 (197)

0.730b

Initial creatinine (mg/dL)

3.04 +/- 2.72 (195)

2.73 +/- 3.28 (197)

0.115c

Initial hematocrit (%)

31.6 +/- 6.6 (197)

33.1 +/- 8.1 (197)

0.046 b

Initial WBC (x103 ul)

15.1 +/- 9.7 (196)

16.4 +/- 15.6 (197)

0.294b

Initial platelet count (x103 ul)

234 +/- 138 (195)

231 +/- 153 (196)

0.844b

Initial lactate (mmol/L)

3.4 +/- 3.0 (196)

4.1 +/- 3.5 (195)

0.019 c

Initial glucose (mg/dL)

136 +/- 98 (197)

136 +/- 52 (197)

0.960b

Initial 24-hour fluid volume (ml)

4,005 +/- 2,763 (190)

4,378 +/- 3,040 (192)

0.321c

Receipt of vasoactive agents

88 (197)

79 (197)

0.415a

  1. Significance, P <0.05; aChi-square test; bStudent’s t-test; cMann-Whitney U test. APACHE II, Acute Physiology and Chronic Health Evaluation II; CVP, central venous pressure; LVEF, left ventricular ejection fraction; MAP, mean arterial pressure; PO2/FiO2, partial pressure of oxygen to the fraction of inspired oxygen; ScVO2, mixed venous oxygen saturation; WBC, white blood count.