Variable | Cases (n) | Controls (n) | P |
---|---|---|---|
Age (years) | 68 +/- 16 (197) | 67 +/- 16 (197) | 0.935b |
Male gender | 129 (197) | 129 (197) | 1.000a |
LVEF (%) | 35 +/- 12 (197) | 60 +/- 5 (197) | <0.001 b |
APACHE II | 20 +/- 7 (194) | 19 +/- 8 (191) | 0.603b |
Initial CVP (cm H2O) | 9 +/- 8 (128) | 8 +/- 7 (120) | 0.334b |
ScVO2 (%) | 67 +/- 17 (166) | 71 +/- 16 (166) | 0.009 b |
Lung Infection | 64 (197) | 54 (197) | 0.322a |
Sepsis bundle compliant | 61 (197) | 69 (197) | 0.453a |
MAP <65Â mm Hg | 116 (197) | 114 (197) | 0.919a |
Initial temperature (°C) | 36.9 +/- 1.6 (196) | 37.0 +/- 1.5 (195) | 0.714b |
Temperature at 24 hours (°C) | 37.2 +/- 2.0 (197) | 37.3 +/- 2.0 (197) | 0.471b |
Initial heart rate (min−1) | 104 +/- 27 (197) | 108 +/- 24 (197) | 0.074b |
Heart rate at 24 hours (min−1) | 115 +/- 32 (197) | 117 +/- 29 (197) | 0.360b |
Initial respiratory rate (min−1) | 24 +/- 9 (197) | 24 +/- 9 (197) | 0.558b |
Respiratory rate at 24 hours (min−1) | 29 +/- 9 (197) | 30 +/- 9 (197) | 0.435b |
Initial MAP (mm Hg) | 74 +/- 22 (197) | 76 +/- 23 (197) | 0.502b |
MAP at 24Â hours (mm Hg) | 58 +/- 19 (197) | 60 +/- 21 (197) | 0.226b |
Initial pH | 7.35 +/- 0.12 (176) | 7.35 +/- 0.13 (175) | 0.994b |
pH at 24Â hours | 7.31 +/- 0.13 (112) | 7.29 +/- 0.15 (107) | 0.302b |
Initial PO2/FiO2 | 259 +/- 130 (161) | 266 +/- 139 (166) | 0.630b |
PO2/FiO2 at 24Â hours | 265 +/- 113 (108) | 268 +/- 126 (115) | 0.846b |
Initial sodium (mg/dL) | 139 +/- 7 (196) | 139 +/- 12 (197) | 0.730b |
Initial creatinine (mg/dL) | 3.04 +/- 2.72 (195) | 2.73 +/- 3.28 (197) | 0.115c |
Initial hematocrit (%) | 31.6 +/- 6.6 (197) | 33.1 +/- 8.1 (197) | 0.046 b |
Initial WBC (x103 ul) | 15.1 +/- 9.7 (196) | 16.4 +/- 15.6 (197) | 0.294b |
Initial platelet count (x103 ul) | 234 +/- 138 (195) | 231 +/- 153 (196) | 0.844b |
Initial lactate (mmol/L) | 3.4 +/- 3.0 (196) | 4.1 +/- 3.5 (195) | 0.019 c |
Initial glucose (mg/dL) | 136 +/- 98 (197) | 136 +/- 52 (197) | 0.960b |
Initial 24-hour fluid volume (ml) | 4,005 +/- 2,763 (190) | 4,378 +/- 3,040 (192) | 0.321c |
Receipt of vasoactive agents | 88 (197) | 79 (197) | 0.415a |