No anticoagulation | Heparin | Citrate | ||
---|---|---|---|---|
n = 13 | n = 8 | n = 21 | P | |
Sex, male | 7 (54) | 6 (75) | 14 (75) | 0.59 |
Age, years | 70 (34–84) | 57 (23–81) | 64 (32–84) | 0.49 |
Weight, kg | 70 (50–100) | 74 (55–135) | 78 (60–110) | 0.41 |
Reason for admission | 0.29 | |||
Respiratory | 2 (15) | 5 (63) | 7 (33) | |
Circulatory | 3 (23) | 1 (13) | 4 (19) | |
Trauma | 2 (15) | 0 | 1 (5) | |
Post-CPR | 2 (15) | 0 | 2 (10) | |
Postoperative | 4 (31) | 1 (13) | 7 (33) | |
AKI | 0 | 1 (13) | 0 | |
Vasopressor dependent | 13 (100) | 6 (75) | 16 (76) | 0.15 |
Mechanical ventilation | 11(85) | 8 (100) | 19 (91) | 0.51 |
Sepsis | 5 (39) | 5 (63) | 8 (38) | 0.46 |
APACHE II at ICU admission | 28 (11–42) | 22 (15–37) | 25 (14–41) | 0.47 |
SAPS II at ICU admission | 75 (43–112) | 47 (37–77) | 52 (32–86) | 0.002 |
SOFA at ICU admission | 14 (7–21) | 11 (8–15) | 13 (8–18) | 0.02 |
ICU stay, days | 5 (2–82) | 20 (4–48) | 20 (3–81) | 0.08 |
LOS in ICU at start CVVH, days | 1 (1–5) | 2 (1–4) | 2 (0–14) | 0.74 |
Biochemical data | ||||
Creatinine at start, μΜ | 249 (100–410) | 420 (156–626) | 326 (47–622) | 0.01 |
Creatinine 24 hours, μM | 206 (140–250) | 284 (125–463) | 232 (46–441) | 0.05 |
Urea at start, mM | 21 (6–48) | 32 (12–97) | 21 (6–41) | 0.25 |
Urea 24 hours, mM | 17 (6–34) | 17 (11–102) | 14 (6–28) | 0.24 |
Leukocytes at start, ×109 | 8 (1–17) | 12 (7–20) | 12 (1–26) | 0.29 |
Leukocytes 24 hours, ×109 | 10 (1–26) | 13 (6–26) | 11 (2–28) | 0.85 |
Platelets at start, ×109 | 65 (22–173) | 167 (44–352) | 118 (35–332) | 0.03 |
Platelets 24 hours, ×109 | 59 (13–148) | 117 (27–239) | 105 (5–349) | 0.02 |