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Table 1 Patient characteristics

From: The plasma level and biomarker value of neutrophil gelatinase-associated lipocalin in critically ill patients with acute kidney injury are not affected by continuous venovenous hemofiltration and anticoagulation applied

 

No anticoagulation

Heparin

Citrate

 

n = 13

n = 8

n = 21

P

Sex, male

7 (54)

6 (75)

14 (75)

0.59

Age, years

70 (34–84)

57 (23–81)

64 (32–84)

0.49

Weight, kg

70 (50–100)

74 (55–135)

78 (60–110)

0.41

Reason for admission

   

0.29

 Respiratory

2 (15)

5 (63)

7 (33)

 

 Circulatory

3 (23)

1 (13)

4 (19)

 

 Trauma

2 (15)

0

1 (5)

 

 Post-CPR

2 (15)

0

2 (10)

 

 Postoperative

4 (31)

1 (13)

7 (33)

 

 AKI

0

1 (13)

0

 

Vasopressor dependent

13 (100)

6 (75)

16 (76)

0.15

Mechanical ventilation

11(85)

8 (100)

19 (91)

0.51

Sepsis

5 (39)

5 (63)

8 (38)

0.46

APACHE II at ICU admission

28 (11–42)

22 (15–37)

25 (14–41)

0.47

SAPS II at ICU admission

75 (43–112)

47 (37–77)

52 (32–86)

0.002

SOFA at ICU admission

14 (7–21)

11 (8–15)

13 (8–18)

0.02

ICU stay, days

5 (2–82)

20 (4–48)

20 (3–81)

0.08

LOS in ICU at start CVVH, days

1 (1–5)

2 (1–4)

2 (0–14)

0.74

Biochemical data

    

Creatinine at start, μΜ

249 (100–410)

420 (156–626)

326 (47–622)

0.01

Creatinine 24 hours, μM

206 (140–250)

284 (125–463)

232 (46–441)

0.05

Urea at start, mM

21 (6–48)

32 (12–97)

21 (6–41)

0.25

Urea 24 hours, mM

17 (6–34)

17 (11–102)

14 (6–28)

0.24

Leukocytes at start, ×109

8 (1–17)

12 (7–20)

12 (1–26)

0.29

Leukocytes 24 hours, ×109

10 (1–26)

13 (6–26)

11 (2–28)

0.85

Platelets at start, ×109

65 (22–173)

167 (44–352)

118 (35–332)

0.03

Platelets 24 hours, ×109

59 (13–148)

117 (27–239)

105 (5–349)

0.02

  1. Median (and range) or number (percentage). AKI, acute kidney injury; APACHE II, Acute Physiology and Chronic Health Evaluation II; CRP, cardiopulmonary resuscitation; ICU, intensive care unit; LOS, length of stay; SAPS II, Simplified Acute Physiology Score II; SOFA, Sequential Organ Failure Assessment score.