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Table 1 Patient characteristics

From: The plasma level and biomarker value of neutrophil gelatinase-associated lipocalin in critically ill patients with acute kidney injury are not affected by continuous venovenous hemofiltration and anticoagulation applied

  No anticoagulation Heparin Citrate
  n = 13 n = 8 n = 21 P
Sex, male 7 (54) 6 (75) 14 (75) 0.59
Age, years 70 (34–84) 57 (23–81) 64 (32–84) 0.49
Weight, kg 70 (50–100) 74 (55–135) 78 (60–110) 0.41
Reason for admission     0.29
 Respiratory 2 (15) 5 (63) 7 (33)  
 Circulatory 3 (23) 1 (13) 4 (19)  
 Trauma 2 (15) 0 1 (5)  
 Post-CPR 2 (15) 0 2 (10)  
 Postoperative 4 (31) 1 (13) 7 (33)  
 AKI 0 1 (13) 0  
Vasopressor dependent 13 (100) 6 (75) 16 (76) 0.15
Mechanical ventilation 11(85) 8 (100) 19 (91) 0.51
Sepsis 5 (39) 5 (63) 8 (38) 0.46
APACHE II at ICU admission 28 (11–42) 22 (15–37) 25 (14–41) 0.47
SAPS II at ICU admission 75 (43–112) 47 (37–77) 52 (32–86) 0.002
SOFA at ICU admission 14 (7–21) 11 (8–15) 13 (8–18) 0.02
ICU stay, days 5 (2–82) 20 (4–48) 20 (3–81) 0.08
LOS in ICU at start CVVH, days 1 (1–5) 2 (1–4) 2 (0–14) 0.74
Biochemical data     
Creatinine at start, μΜ 249 (100–410) 420 (156–626) 326 (47–622) 0.01
Creatinine 24 hours, μM 206 (140–250) 284 (125–463) 232 (46–441) 0.05
Urea at start, mM 21 (6–48) 32 (12–97) 21 (6–41) 0.25
Urea 24 hours, mM 17 (6–34) 17 (11–102) 14 (6–28) 0.24
Leukocytes at start, ×109 8 (1–17) 12 (7–20) 12 (1–26) 0.29
Leukocytes 24 hours, ×109 10 (1–26) 13 (6–26) 11 (2–28) 0.85
Platelets at start, ×109 65 (22–173) 167 (44–352) 118 (35–332) 0.03
Platelets 24 hours, ×109 59 (13–148) 117 (27–239) 105 (5–349) 0.02
  1. Median (and range) or number (percentage). AKI, acute kidney injury; APACHE II, Acute Physiology and Chronic Health Evaluation II; CRP, cardiopulmonary resuscitation; ICU, intensive care unit; LOS, length of stay; SAPS II, Simplified Acute Physiology Score II; SOFA, Sequential Organ Failure Assessment score.