|
No anticoagulation
|
Heparin
|
Citrate
|
---|
|
n = 13
|
n = 8
|
n = 21
|
P
|
---|
Sex, male
|
7 (54)
|
6 (75)
|
14 (75)
|
0.59
|
Age, years
|
70 (34–84)
|
57 (23–81)
|
64 (32–84)
|
0.49
|
Weight, kg
|
70 (50–100)
|
74 (55–135)
|
78 (60–110)
|
0.41
|
Reason for admission
| | | |
0.29
|
Respiratory
|
2 (15)
|
5 (63)
|
7 (33)
| |
Circulatory
|
3 (23)
|
1 (13)
|
4 (19)
| |
Trauma
|
2 (15)
|
0
|
1 (5)
| |
Post-CPR
|
2 (15)
|
0
|
2 (10)
| |
Postoperative
|
4 (31)
|
1 (13)
|
7 (33)
| |
AKI
|
0
|
1 (13)
|
0
| |
Vasopressor dependent
|
13 (100)
|
6 (75)
|
16 (76)
|
0.15
|
Mechanical ventilation
|
11(85)
|
8 (100)
|
19 (91)
|
0.51
|
Sepsis
|
5 (39)
|
5 (63)
|
8 (38)
|
0.46
|
APACHE II at ICU admission
|
28 (11–42)
|
22 (15–37)
|
25 (14–41)
|
0.47
|
SAPS II at ICU admission
|
75 (43–112)
|
47 (37–77)
|
52 (32–86)
|
0.002
|
SOFA at ICU admission
|
14 (7–21)
|
11 (8–15)
|
13 (8–18)
|
0.02
|
ICU stay, days
|
5 (2–82)
|
20 (4–48)
|
20 (3–81)
|
0.08
|
LOS in ICU at start CVVH, days
|
1 (1–5)
|
2 (1–4)
|
2 (0–14)
|
0.74
|
Biochemical data
| | | | |
Creatinine at start, μΜ
|
249 (100–410)
|
420 (156–626)
|
326 (47–622)
|
0.01
|
Creatinine 24 hours, μM
|
206 (140–250)
|
284 (125–463)
|
232 (46–441)
|
0.05
|
Urea at start, mM
|
21 (6–48)
|
32 (12–97)
|
21 (6–41)
|
0.25
|
Urea 24 hours, mM
|
17 (6–34)
|
17 (11–102)
|
14 (6–28)
|
0.24
|
Leukocytes at start, ×109
|
8 (1–17)
|
12 (7–20)
|
12 (1–26)
|
0.29
|
Leukocytes 24 hours, ×109
|
10 (1–26)
|
13 (6–26)
|
11 (2–28)
|
0.85
|
Platelets at start, ×109
|
65 (22–173)
|
167 (44–352)
|
118 (35–332)
|
0.03
|
Platelets 24 hours, ×109
|
59 (13–148)
|
117 (27–239)
|
105 (5–349)
|
0.02
|
- Median (and range) or number (percentage). AKI, acute kidney injury; APACHE II, Acute Physiology and Chronic Health Evaluation II; CRP, cardiopulmonary resuscitation; ICU, intensive care unit; LOS, length of stay; SAPS II, Simplified Acute Physiology Score II; SOFA, Sequential Organ Failure Assessment score.