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Table 3 Predictive ability of the four components of the PIRO system

From: Risk stratification and prognostic performance of the predisposition, infection, response, and organ dysfunction (PIRO) scoring system in septic patients in the emergency department: a cohort study

Outcome variable Predictor B SE Wald P value OR 95% CI for OR
        5% 95%
ICU admission Predisposition 0.387 0.140 7.591 0.006 1.472 1.118 1.939
  Infection 0.440 0.210 4.382 0.036 1.553 1.028 2.344
  Response 0.364 0.093 15.351 0.000 1.439 1.200 1.727
  Organ dysfunction 0.665 0.058 132.428 0.000 1.944 1.736 2.177
  Constant −7.743 1.031 56.440 0.000 0.000   
MOD Predisposition 0.409 0.110 13.872 0.000 1.506 1.214 1.867
  Infection 0.378 0.166 5.228 0.022 1.460 1.056 2.020
  Response −0.125 0.073 2.907 0.088 0.883 0.764 1.019
  Organ dysfunction 0.544 0.044 154.852 0.000 1.723 1.582 1.878
  Constant −4.272 0.727 34.553 0.000 0.014   
28-day mortality Predisposition 0.225 0.112 4.060 0.044 1.253 1.006 1.560
  Infection −0.017 0.144 0.014 0.904 0.983 0.741 1.303
  Response −0.331 0.073 20.345 0.000 0.718 0.622 0.829
  Organ dysfunction 0.410 0.037 125.453 0.000 1.507 1.403 1.620
  Constant −1.906 0.591 10.391 0.001 0.149   
  1. CI, confidence interval; MOD, multiple organ dysfunction; OR, odds ratio; PIRO, predisposition, infection, response, and organ dysfunction; SE, standard error.