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Table 1 Criteria of the PIRO system

From: Risk stratification and prognostic performance of the predisposition, infection, response, and organ dysfunction (PIRO) scoring system in septic patients in the emergency department: a cohort study

Variable 0 1 2 3 4
Predisposition      
  Age (years) <65 65 to 80 >80   
  COPD   Yes    
  Liver disease    Yes   
  Nursing home resident    Yes   
  Malignancy   Without metastases With metastases   
Infection      
  Skin/soft tissue infection Yes     
  Any other infection    Yes   
  Pneumonia      Yes
Response      
  Respiratory rate (bpm)     >20  
  Bands   >5%    
  Heart rate (bpm)    >120   
Organ dysfunction      
  SBP (mmHg) >90   70 to 90   <70
  BUN (mmol/l)    >7.1   
  Respiratory failure/hypoxemia     Yes  
  Lactate (mmol/l)     >4.0  
  Platelet count (×109/l)    <150   
  1. BUN, blood urea nitrogen; COPD, chronic obstructive pulmonary disease; PIRO, predisposition, infection, response, and organ dysfunction; SBP, systolic blood pressure.