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Table 1 Criteria of the PIRO system

From: Risk stratification and prognostic performance of the predisposition, infection, response, and organ dysfunction (PIRO) scoring system in septic patients in the emergency department: a cohort study

Variable

0

1

2

3

4

Predisposition

     

  Age (years)

<65

65 to 80

>80

  

  COPD

 

Yes

   

  Liver disease

  

Yes

  

  Nursing home resident

  

Yes

  

  Malignancy

 

Without metastases

With metastases

  

Infection

     

  Skin/soft tissue infection

Yes

    

  Any other infection

  

Yes

  

  Pneumonia

    

Yes

Response

     

  Respiratory rate (bpm)

   

>20

 

  Bands

 

>5%

   

  Heart rate (bpm)

  

>120

  

Organ dysfunction

     

  SBP (mmHg)

>90

 

70 to 90

 

<70

  BUN (mmol/l)

  

>7.1

  

  Respiratory failure/hypoxemia

   

Yes

 

  Lactate (mmol/l)

   

>4.0

 

  Platelet count (×109/l)

  

<150

  
  1. BUN, blood urea nitrogen; COPD, chronic obstructive pulmonary disease; PIRO, predisposition, infection, response, and organ dysfunction; SBP, systolic blood pressure.