Table 2 Endogenous rate of appearance (R a ) for phenylalanine (Phe) and glutamine (Gln) and calculated origin of produced glutamine in critically ill patients (n = 11) fully fed, with and without intravenous glutamine supplementation
Baseline fed | Fed and Gln supplemented | P-value | |
|---|---|---|---|
Endogenous Ra Phe (μmol/kg/minute) | 1.22 ± 0.31 | 1.36 ± 0.52 | 0.326 |
Endogenous Ra Gln (μmol/kg/minute) | 7.11 ± 1.90 | 8.08 ± 1.53 | 0.009 |
Gln from protein breakdown (μmol/kg/minute) | 1.08 ± 0.27 | 1.20 ± 0.43 | 0.336 |
Gln from de novo synthesis (μmol/kg/minute) | 6.02 ± 1.82 | 6.89 ± 1.24 | 0.025 |