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Table 1 Patient demographics and baseline characteristics

From: Continuous venovenous hemofiltration versus extended daily hemofiltration in patients with septic acute kidney injury: a retrospective cohort study

 

CVVHF (n = 65)

EDHF (n = 80)

P-value

Age, years

67.78 ± 17.55

68.59 ± 14.97

0.407

Female, n (%)

16 (24.62)

21 (26.25)

0.822

Hypertension, n (%)

25 (38.46)

26 (32.50)

0.455

Diabetes mellitus, n (%)

19 (29.23)

19 (23.75)

0.455

Chronic kidney disease, n (%)

10 (15.38)

15 (18.75)

0.594

Congestive heart failure, n (%)

18 (27.69)

17 (21.25)

0.367

Mechanical ventilation, n (%)

28 (43.08)

31 (38.75)

0.598

Reason for admission

   

  Medical, n (%)

49 (75.39)

58 (72.50)

0.694

  Surgical, n (%)

16 (24.61)

22 (27.50)

 

Se-psis type

   

  Severe sepsis, n (%)

44 (67.69)

65 (81.25)

0.060

  Septic shock, n (%)

21 (32.31)

15 (18.75)

 

Classification of AKI

   

  Risk, n (%)

12 (18.46)

13 (16.25)

0.936

  Injury, n (%)

25 (38.46)

31 (38.75)

 

  Failure, n (%)

28 (43.08)

36 (45.00)

 

  Oliguria, n (%)

48 (73.85)

47 (58.75)

0.057

Median time from AKI occurrence to initiation of RRT, days

3.32 ± 2.06

3.78 ± 2.23

0.277

MAP, mm Hg

65.18 ± 17.49

73.69 ± 17.21

0.037

Respiratory rate, breaths/minute

23.03 ± 7.08

22.94 ± 10.05

0.482

Heart rate, beats/minute

103.78 ± 19.09

99.80 ± 22.58

0.187

Temperature, °C

37.55 ± 1.47

37.40 ± 1.22

0.301

Serum urea, mmol/L

28.79 ± 16.61

32.66 ± 13.38

0.113

Serum creatinine, μmol/L

399.30 ± 240.71

443.42 ± 218.29

0.182

eGFR, ml/minute

17.89 ± 15.32

13.98 ± 13.58

0.102

PH

7.22 ± 0.14

7.27 ± 0.13

0.036

HCO3- mmol/L

14.99 ± 5.39

16.79 ± 5.43

0.061

Lactate, meq/L

3.98 ± 1.32

3.21 ± 1.91

0.330

Serum sodium, mmol/L

137.37 ± 10.40

139.71 ± 11.45

0.159

Serum potassium, mmol/L

4.53 ± 1.13

4.49 ± 1.13

0.444

White blood-cell count, 109/L

15.43 ± 7.07

14.28 ± 7.10

0.209

Platelet count, 109/L

137.67 ± 80.82

147.53 ± 95.62

0.314

CRP, ng/dl

95.44 ± 66.59

85.19 ± 56.59

0.216

APACHE II score

31.10 ± 7.23

31.20 ± 7.12

0.472

SOFA organ-system score

11.98 ± 2.92

12.29 ± 3.05

0.213

  1. AKI, acute kidney injury; RRT, renal replacement therapy; MAP, mean arterial pressure; eGFR, estimated glomerular filtration rate; HCO3-, bicarbonate; CRP, C-reactive protein; APACHE II, acute physiologic and chronic health evaluation; SOFA, sequential organ failure assessment; CVVHDF, continuous venovenous hemodiafiltration; CVVHF, continuous venovenous hemofiltration.