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Table 4 Summary of multivariable logistic regression analysis with in-hospital death as the dependent variable a

From: Adjuvant selenium supplementation in the form of sodium selenite in postoperative critically ill patients with severe sepsis

Variables

Univariate analysis

Multivariable analysis

 

OR (95% CI)

P-value

OR (95% CI)

P-value

Adjuvant selenium

1.33 (1.03 to 1.71)

0.027

1.19 (0.86 to 1.65)

0.288

Age (per year)

1.03 (1.02 to 1.71)

<0.001

1.02 (1.01 to 1.04)

0.001

Sex

1.46 (0.95 to 1.65)

0.005

1.20 (0.88 to 1.65)

0.249

SAPS II score

1.09 (1.03 to 1.18)

<0.001

1.02 (1.01 to 1.03)

0.003

Type of surgery

Gastrointestinal

2.19 (0.79 to 2.42)

<0.001

0.05 (0.24 to 1.04)

0.065

 Cardiothoracic

0.68 (0.53 to 1.25)

<0.001

0.36 (0.18 to 0.75)

0.006

 Trauma

1.16 (0.68 to 3.08)

0.224

0.61 (0.23 to 1.61)

0.321

 Others

0.64 (0.5 to 0.85)

0.008

0.44 (0.21 to 0.93)

0.031

Comorbidities

 Arterial hypertension

0.88 (0.05 to 1.22)

0.369

1.02 (0.75 to 1.38)

0.926

 Diabetes mellitus

0.93 (0.04 to 2.55)

0.621

0.77 (0.55 to 1.08)

0.129

 Cancer

2.35 (1.76 to 3.06)

<0.001

2.12 (1.50 to 2.99)

<0.001

 Cirrhosis

1.27 (1.07 to 2.57)

<0.001

2.63 (1.40 to 4.94)

0.037

 Chronic renal failure

1.30 (1.29 to 1.75)

0.160

1.62 (1.03 to 2.55)

0.037

Source of sepsis

 Respiratory

0.96 (0.53 to 1.12)

<0.001

0.88 (0.40 to 1.91)

0.738

 Gastrointestinal

1.02 (0.99 to 2.47)

<0.001

1.64 (0.73 to 3.67)

0.227

 Cardiothoracic

0.99 (0.58 to 1.00)

0.090

1.01 (0.35 to 2.91)

0.985

 Wound

0.99 (0.60 to 1.01)

0.177

0.59 (0.19 to 1.85)

0.362

 Urogenital

0.997 (0.38 to 1.0)

0.057

0.32 (0.08 to 1.2)

0.090

 Bloodstream

1.02 (1.01 to 1.16)

0.806

1.54 (0.34 to 6.86)

0.574

SOFA subscores (per point)

 SOFA resp

0.89 (0.46 to 1.08)

0.053

1.01 (0.91 to 1.13)

0.807

 SOFA coag

1.26 (0.87 to 1.44)

0.001

1.18 (0.99 to 1.4)

0.063

 SOFA liver

1.78 (1.44 to 3.1)

0.001

1.18 (0.98 to 1.40)

0.075

 SOFA CVS

1.09 (0.90 to 1.87)

0.060

1.00 (0.89 to 1.12)

0.995

 SOFA CNS

1.92 (1.02 to 3.19)

0.631

0.97 (0.86 to 1.08)

0.531

 SOFA ren

1.26 (0.28 to 1.32)

<0.001

1.14 (0.96 to 1.35)

0.148

Blood lactate (mg/dl)

1.08 (0.88 to 1.09)

<0.001

1.07 (1.03 to 1.12)

0.002

  1. aCI: Confidence interval; CNS: Central nervous system; coag: Coagulation; CVS: Cardiovascular system; OR: Odds ratio; ren: Renal; resp: Respiration; SAPS II: Simplified Acute Physiology Score II; SOFA: Sequential Organ Failure Assessment.