Intensive care unit depth of sleep: proof of concept of a simple electroencephalography index in the non-sedated

Table 3 ICU patient characteristics

Patient	A	B	C	D	E
Sex	F	F	M	M	F
BMI	25 to 30	20 to 25	30 to 35	20 to 25	>35
Age range, years	60 to 70	50 to 60	60 to 70	60 to 70	40 to 50
Days prior on ICU	2	2	9	10	2
Duration of inclusion, days	1.81	2.98	2.94	0.99	0.93
APACHE II^a	14	35	-	17	9
APACHE IV^b	58	98	45	54	30
TISS 76, mean^c	15.5	32	19	8.5	17.6
Diagnosis on admittance	TTP	Bacterial pneumonia	Viral pneumonia	Bacterial pneumonia	Arterial thrombus
Mechanical ventilation, days	0	1	1	0	0
Length of ICU stay, days	3	10	13	30	5
Medication, per recording day, median Benzodiazepines, mg (Lorazepam eqv.)	0.3	0.5	0.3	0	1.8
Opioids, mg (morphine eqv.)	1.3	8	24.3	0	21.3
Propofol 2%, ml	0	38	0	0	0

^aAcute Physiology and Chronic Health Evaluation (APACHE) II is a severity of illness scoring system, with scores ranging from 0 (best) to 71 (worst). All scores were determined using the most abnormal values in the first 24 hours of ICU admission. ^bAPACHE IV is a severity of illness scoring system, with scores ranging from 0 (best) to 150 (worst). All scores were determined using the most abnormal values in the first 24 hours of ICU admission. ^cTherapeutic Intervention Scoring System (TISS 76) quantifies nursing workload into four classes depending on 76 points of therapeutic intervention. The mean is calculated from daily scores. BMI, body mass index; TTP, thrombotic thrombocytopenic purpura.

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