From: Hemostasis during the early stages of trauma: comparison with disseminated intravascular coagulation
 | Non-DIC | JAAM DIC | P value | |
---|---|---|---|---|
(n = 137) | ISTH (−) (n = 131) | ISTH (+) (n = 70) | ||
Age (years) | 48 ± 20 | 47 ± 23 | 47 ± 24 | 0.862 |
Sex (male/female) | 40/97 | 46/85 | 32/38 | 0.062 |
Injury severity score | 22.1 ± 12.1 | 27.9 ± 13.4 | 37.5 ± 12.2 | 0.000 |
APACHE II score | 15.6 ± 7.5 | 21.6 ± 8.4 | 26.4 ± 8.3 | 0.000 |
SOFA score | 5.6 ± 2.9 | 7.4 ± 3.6 | 10.9 ± 3.6 | 0.000 |
SIRS criteria | 2.9 ± 0.9 | 3.3 ± 0.7 | 3.0 ± 0.9 | 0.000 |
JAAM DIC score | 1.6 ± 0.9 | 4.7 ± 0.9 | 6.3 ± 1.3 | 0.000 |
ISTH DIC score | 1.3 ± 1.2 | 3.2 ± 0.7 | 6.0 ± 0.9 | 0.000 |
MODS (yes/no) | 4/133 | 26/105 | 31/39 | 0.000 |
Outcome (survived/died) | 127/10 | 100/31 | 36/34 | 0.000 |
FDP/D-dimer ratio | 1.8 ± 1.1 | 1.9 ± 0.7 | 5.3 ± 23.8 | 0.002 |
FFP/PRBC transfusion ratio | 0.7 ± 0.4 | 1.0 ± 0.9 | 1.1 ± 0.9 | 0.073 |
Lactate (mM) | 3.6 ± 2.6 | 4.8 ± 3.5 | 7.8 ± 4.9 | 0.000 |
Platelet concentrate (U) | 3.4 ± 9.1 | 4.5 ± 10.2 | 23.0 ± 24.8 | 0.000 |
Packed red blood cells (ml) | 247 ± 708 | 666 ± 1,442 | 2,655 ± 3,180 | 0.000 |
Fresh frozen plasma (ml) | 159 ± 431 | 575 ± 1,101 | 2,275 ± 2,586 | 0.000 |
Massive transfusion (yes/no) | 11/126 | 29/102 | 48/22 | 0.000 |