| BASELINE | END | END | |||
---|---|---|---|---|---|---|
 | LVT/OLPEEP n = 14 | HVT/OLPEEP n = 14 | NBD | BD | ||
LVT/OLPEEP n = 7 | HVT/LPEEP n = 6 | LVT/OLPEEP n = 7 | HVT/LPEEP n = 4 | |||
VT (ml/kg) | 6.1 ± 0.3 + | 11.9 ± 0.2 | 5.9 ± 0.2 * | 12.2 ± 0.3 | 6.0 ± 0.3 # | 11.9 ± 0.2 |
PEEP (cmH2O) | 5.0 ± 1.0 + | 2.0 ± 0.1 | 4.75 ± 1.0 * | 1.99 ± 0.0 | 5.2 ± 1.1 # | 2.0 ± 0.0 |
Pinsp (cmH2O) | 12.6 ± 1.5 + | 16.5 ± 2.4 | 15.0 ± 2.2 * | 18.8 ± 4.8 | 15.0 ± 0.9 # | 23 ± 7.6 |
Pmean (cmH2O) | 7.9 ± 1.1 + | 6.0 ± 1.1 | 8.3 ± 1.1 | 8.7 ± 2.0 | 9.0 ± 0.9 | 10.3 ± 2.7 |
RR (bpm) | 100.3 ± 2.9 + | 31.4 ± 2.4 | 108.1 ± 5.3 *‡ | 30.6 ± 4.2 | 102.3 ± 4.4 # | 29.2 ± 3.8 |
Estat, RS (cmH2O.ml−1) | 2.41 ± 0.4 | 2.39 ± 0.4 | 3.42 ± 0.9 | 2.74 ± 0.9 | 3.06 ± 0.4 | 3.44 ± 1.2 |
Estat, L (cmH2O.ml−1) | 1.83 ± 0.4 | 1.9 ± 0.4 | 2.59 ± 1.0 | 2.23 ± 0.9 | 2.29 ± 0.4 | 2.90 ± 1.2 |
Estat, CW (cmH2O.ml−1) | 0.58 ± 0.2 | 0.37 ± 0.2 | 0.49 ± 0.3 | 0.31 ± 0.1 | 0.76 ± 0.3 | 0.50 ± 0.2 |
PaO2/FiO2 | 439.2 ± 47.4 | 463.8 ± 32.5 | 458.8 ± 44.9 | 410.2 ± 129.9 | 470.5 ± 26.7 # | 321.6 ± 120.0 |
PaCO2 (mmHg) | 47.5 ± 9.7 | 41.2 ± 8.6 | 47.6 ± 12.1 | 37.5 ± 5.6 | 39.0 ± 4.5 | 37.35 ± 5.6 |
pHa | 7.34 ± 0.0 | 7.34 ± 0.0 | 7.34 ± 0.1 ‡ | 7.38 ± 0.0 | 7.42 ± 0.0 | 7.41 ± 0.1 |
HR (bpm) | 255.4 ± 40.6 | 284.0 ± 42.7 | 230.5 ± 60.0 ‡ | 262.5 ± 31.1 | 292.5 ± 52.6 | 314.0 ± 90.9 |
MAP (mmHg) | 63.2 ± 11.4 | 70.5 ± 8.8 | 75.9 ± 10.6 ‡ | 72.4 + 20.3 $ | 64.6 ± 8.7 | 51.6 ± 14.1 |