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Table 5 Univariate Cox proportional hazards models for 28-day and 6-month mortality for patients admitted to the ICU with CAP

From: Patients with community acquired pneumonia admitted to European intensive care units: an epidemiological survey of the GenOSept cohort

  Increment 28-day mortality 6-month mortality
   Hazard ratio 95% CI P-value Hazard ratio 95% CI P-value
APACHE II score   1.1 1.08, 1.12 <1E-14 1.08 1.07-1.1 0.00E + 00
Staphylococcus aureus   1.65 0.99, 2.75 5.59E-02 2.03 1.38, 2.97 3.02E-04
Haematocrit % 0.95 0.93, 0.98 2.98E-05 0.96 0.94, 0.98 6.19E-06
pH value 0.1 unit 0.7 0.62, 0.77 2.31E-11 0.75 0.69, 0.82 1.81E-10
Septic shock   1.98 1.48, 2.64 3.61E-06 1.6 1.28, 2 3.92E-05
Diffuse bilateral change on CXR   1.27 0.94, 1.7 1.14E-01 1.54 1.22, 1.94 2.44E-04
Bilirubin 10 μmol/L 1.04 1.02, 1.07 8.64E-04 1.04 1.02, 1.07 2.86E-04
Creatinine day 1 10 μmol/L 1.02 1.01, 1.03 1.41E-03 1.02 1.01, 1.03 1.85E-04
Lowest heart rate day 1   1.01 1, 1.02 2.35E-03 1.01 1.01, 1.02 4.62E-04
Lowest MAP day 1   0.97 0.96, 0.98 4.96E-06 0.98 0.97, 0.99 1.95E-06
Lowest SBP day 1 mmHg 0.98 0.97, 0.99 7.09E-08 0.98 0.98, 0.99 5.33E-07
Need for any ventilatory support   3.17 1.72, 5.82 2.01E-04 3.63 2.2, 6 5.07E-07
Mechanical ventilation   2.17 1.46, 3.21 1.19E-04 2.21 1.62, 3.03 6.41E-07
Renal failure in week 1   1.99 1.5, 2.64 2.04E-06 1.65 1.32, 2.07 1.40E-05
Need for renal replacement week 1   2.45 1.8, 3.32 9.00E-09 2.2 1.71, 2.82 6.09E-10
SOFAday1   1.12 1.08, 1.17 2.14E-08 1.11 1.08, 1.15 3.22E-10
Urine volume day 1 100 mL/day 0.97 0.96, 0.99 1.09E-04 0.97 0.96, 0.98 3.90E-06
  1. All values are significant at a type I error rate of 5% after a Bonferroni correction to take account of the multiple testing of 64 variables (a P-value <0.00078 was considered to be statistically significant). Results are adjusted for age and sex. All day-1 variables unless specified otherwise. RRT, renal replacement therapy; MV, mechanical ventilation; NIV, non-invasive ventilation; SBP, systolic blood pressure; MAP, mean arterial pressure.