Use of probiotics in the treatment of severe acute pancreatitis: a systematic review and meta-analysis of randomized controlled trials

Table 2 Types of probiotics used in the trials

Trial	Probiotics group	Control group	Length of treatment (days)
Oláh et al. [26]	10⁹Leuconostoc plantarum 299 per serving	10⁹ heat-inactivated L. plantarum 299 per serving	7
	Twice daily	Twice daily
Li et al. [25]	10⁷Bifidobacterium longum, 10⁶L. bulgaricus, and 10⁶Streptococcus thermophilus per serving (Golden Bifid)	Water	7
	Thrice daily	Three times daily
Oláh et al. [27]	10¹⁰Pediococcus pentosaceus, 10¹⁰L. mesenteroides, 10¹⁰L. paracasei and 10¹⁰L. plantarum with bioactive fibers per serving (Synbiotic 2000 Forte; Medifarm, Kågeröd, Sweden)	Bioactive fibers	7
	Once daily	Once daily
Besselink et al. [23]	L. acidophilus, L. casei, L. salivarius, L. lactis, B. bifidum and B. lactis in a totally daily dose of 10¹⁰ (Ecologic 641; Winclove Bio Industries, Amsterdam, the Netherlands)	Placebo	28
	Twice daily	Twice daily
Plaudis et al. [28]	10¹⁰P. pentosaceus, 10¹⁰L. mesenteroides, 10¹⁰L. paracasei and 10¹⁰L. plantarum with bioactive fibers per serving (Synbiotic 2000 Forte)	Bioactive fibers	Unclear
	Twice daily	Twice daily
Cui et al. [24]	4 × 10⁷B. longum, 4 × 10⁷L. bulgaricus and 4 × 10⁷Enterococcus faecalis per serving	Water	14
	Twice daily	Twice daily

ISSN: 1364-8535