Table 2 Primary and secondary end points
Before (9 mo) | Training (10 mo) | AAS (13 mo) | Inclinometer (7 mo) | Oral care (5 mo) | During (35 mo) | P value | |
|---|---|---|---|---|---|---|---|
Pts: 401 | Pts: 453 | Pts: 545 | Pts: 294 | Pts: 242 | Pts: 1,534 | ||
Median length of ICU stay in days (IQR) | 4 (2-7) | 5 (3-7) | 4 (3-6.5) | 4 (2-7) | 4 (3-6) | 4 (3-7) | 0.47 |
Median days on MV (IQR) | 1 (1-1) | 1 (1-1) | 1 (1-1) | 1 (1-1) | 1 (1-1) | 1 (1-1) | 0.37 |
Mean days on VM (SD) | 4.1 (11.9) | 2.7 (5.7) | 3.1 (8.9) | 2.4 (4.6) | 3.1 (9.1) | 2.8 (7.4) | 0.05 |
VAP/1,000 days of MV | 23.9 | 14.8 | 17.8 | 4.8 | 10.9 | 13.5 | 0.005 |
Mean days of MV/1,000 days of stay (SD) | 507 (128) | 412 (103) | 359 (85) | 342 (99) | 390 (77) | 375 (93) | 0.001 |
Primary cost of antimicrobial/1,000 days of stay | €70,612 | €94,839 | €39,564 | €30,153 | €34,671 | €52,775 | 0.10 |
Mortality (%) | 52 (13.0) | 56 (10.4) | 56 (10.3) | 21 (7.1) | 23 (9.5) | 156 (10.2) | 0.10 |