Skip to main content

Table 1 P -values obtained from statistical comparisons between the nonsmoke/nonventilated, ventilation-alone and mechanical ventilation groups a

From: Double impact of cigarette smoke and mechanical ventilation on the alveolar epithelial type II cell

Groups compared

Measurement

P-value

FDR rank

FDR threshold P-value

Significance after FDR correctionb

NSNV vs. SV

Total cell BAL

0.0006

1

0.0023

+

NSNV vs. SV

PMN cell total BAL

0.0013

2

0.0045

+

NSNV vs. SV

BAL Protein

0.0013

3

0.0068

+

NSNV vs. SV

Nuclear HSP70

0.0302

7

0.0159

-

NSNV vs. SV

Membrane TLR4

0.0392

9

0.0205

-

NSNV vs. SV

Cytosolic caspase 8

0.0502

10

0.0227

-

NSNV vs. SV

Nuclear NFκBp65

0.1151

13

0.0295

-

NSNV vs. SV

Cytosolic caspase 9

0.1167

14

0.0318

-

NSNV vs. SV

Nuclear caspase 3

0.1520

16

0.0364

-

NSNV vs. SV

Nuclear DNA fragments

0.3524

19

0.0432

-

NSNV vs. SV

Cytosolic catalase

0.7059

22

0.0500

-

NSV vs. SV

Nuclear DNA fragments

0.0082

4

0.0091

+

NSV vs. SV

PMN cell total BAL

0.0108

5

0.0114

+

NSV vs. SV

Membrane TLR4

0.0176

6

0.0136

-

NSV vs. SV

Cytosolic caspase 8

0.0352

8

0.0182

-

NSV vs. SV

BAL protein

0.0875

11

0.0250

-

NSV vs. SV

Nuclear NFκBp65

0.0897

12

0.0273

-

NSV vs. SV

Nuclear HSP70

0.1228

15

0.0341

-

NSV vs. SV

Nuclear caspase 3

0.1871

17

0.0386

-

NSV vs. SV

Cytosolic caspase 9

0.2767

18

0.0409

-

NSV vs. SV

Cytosolic catalase 8

0.4090

20

0.0455

-

NSV vs. SV

Total cells BAL

0.4549

21

0.0477

-

  1. aBAL: Bronchoalveolar lavage; FDR: False discovery rate; HSP: Heat shock protein; NSNV: Nonsmoke/nonventilated; NSV: Ventilation alone; NFκB: Nuclear factor κB; PMN: Polymorphonuclear; SV: Mechanical ventilation; TLR4: Toll-like receptor 4. bThe right column indicates statistical significance after performing the FDR calculation (+ signifies statistical significance after correction and - means no statistical significance after correction).