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Table 1 P -values obtained from statistical comparisons between the nonsmoke/nonventilated, ventilation-alone and mechanical ventilation groups a

From: Double impact of cigarette smoke and mechanical ventilation on the alveolar epithelial type II cell

Groups compared Measurement P-value FDR rank FDR threshold P-value Significance after FDR correctionb
NSNV vs. SV Total cell BAL 0.0006 1 0.0023 +
NSNV vs. SV PMN cell total BAL 0.0013 2 0.0045 +
NSNV vs. SV BAL Protein 0.0013 3 0.0068 +
NSNV vs. SV Nuclear HSP70 0.0302 7 0.0159 -
NSNV vs. SV Membrane TLR4 0.0392 9 0.0205 -
NSNV vs. SV Cytosolic caspase 8 0.0502 10 0.0227 -
NSNV vs. SV Nuclear NFκBp65 0.1151 13 0.0295 -
NSNV vs. SV Cytosolic caspase 9 0.1167 14 0.0318 -
NSNV vs. SV Nuclear caspase 3 0.1520 16 0.0364 -
NSNV vs. SV Nuclear DNA fragments 0.3524 19 0.0432 -
NSNV vs. SV Cytosolic catalase 0.7059 22 0.0500 -
NSV vs. SV Nuclear DNA fragments 0.0082 4 0.0091 +
NSV vs. SV PMN cell total BAL 0.0108 5 0.0114 +
NSV vs. SV Membrane TLR4 0.0176 6 0.0136 -
NSV vs. SV Cytosolic caspase 8 0.0352 8 0.0182 -
NSV vs. SV BAL protein 0.0875 11 0.0250 -
NSV vs. SV Nuclear NFκBp65 0.0897 12 0.0273 -
NSV vs. SV Nuclear HSP70 0.1228 15 0.0341 -
NSV vs. SV Nuclear caspase 3 0.1871 17 0.0386 -
NSV vs. SV Cytosolic caspase 9 0.2767 18 0.0409 -
NSV vs. SV Cytosolic catalase 8 0.4090 20 0.0455 -
NSV vs. SV Total cells BAL 0.4549 21 0.0477 -
  1. aBAL: Bronchoalveolar lavage; FDR: False discovery rate; HSP: Heat shock protein; NSNV: Nonsmoke/nonventilated; NSV: Ventilation alone; NFκB: Nuclear factor κB; PMN: Polymorphonuclear; SV: Mechanical ventilation; TLR4: Toll-like receptor 4. bThe right column indicates statistical significance after performing the FDR calculation (+ signifies statistical significance after correction and - means no statistical significance after correction).