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Table 6 Evolution of biochemistry parameters during the study period

From: Half-molar sodium lactate infusion improves cardiac performance in acute heart failure: a pilot randomised controlled clinical trial

Time point Na+ K+ Cl- P Crea
Baseline      
  Control (n = 21) 137 ± 5 4.3 ± 0.8 104 ± 5 1.46 ± 0.62 175 ± 107
  Lactate (n = 19) 136 ± 4 4.2 ± 0.7 104 ± 7 1.23 ± 0.46 146 ± 123
6 hours      
  Control (n = 20) 137 ± 5 4.2 ± 0.6 104 ± 4 1.36 ± 0.54 174 ± 124
  Lactate (n = 19) 141 ± 5b,c 3.8 ± 0.4d 100 ± 7b 0.95 ± 0.50b 138 ± 126
12 hours      
  Control (n = 19) 137 ± 6 4.3 ± 0.6 104 ± 5 1.40 ± 0.58 186 ± 135
  Lactate (n = 19) 143 ± 5b,e 3.6 ± 0.4b,e 99 ± 7b 0.96 ± 0.45d 134 ± 123
24 hours      
  Control (n = 19) 138 ± 5 4.3 ± 0.5 104 ± 4 1.30 ± 0.49 168 ± 133
  Lactate (n = 18) 146 ± 6b,e 3.3 ± 0.4b,e 98 ± 9b 0.98 ± 0.40d 136 ± 128
48 hours      
  Control (n = 18) 138 ± 7 4.3 ± 0.4 102 ± 4 1.22 ± 0.33 156 ± 130
  Lactate (n = 18) 144 ± 6b,e 3.8 ± 0.5 103 ± 6 1.15 ± 0.41 129 ± 119
  1. aCl - = Plasma chloride concentration (mmol/L), Crea = Plasma creatinine concentration (μmol/L), K+ = Plasma potassium concentration (mmol/L), Na+ = Plasma sodium concentration (mmol/L), P = Plasma phosphate concentration (mmol/L). bP < 0.01 compared to baseline, cP < 0.05, dP < 0.05, eP < 0.01 intergroup comparison. Data are expressed as mean ± SD.