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Table 6 Evolution of biochemistry parameters during the study period

From: Half-molar sodium lactate infusion improves cardiac performance in acute heart failure: a pilot randomised controlled clinical trial

Time point

Na+

K+

Cl-

P

Crea

Baseline

     

  Control (n = 21)

137 ± 5

4.3 ± 0.8

104 ± 5

1.46 ± 0.62

175 ± 107

  Lactate (n = 19)

136 ± 4

4.2 ± 0.7

104 ± 7

1.23 ± 0.46

146 ± 123

6 hours

     

  Control (n = 20)

137 ± 5

4.2 ± 0.6

104 ± 4

1.36 ± 0.54

174 ± 124

  Lactate (n = 19)

141 ± 5b,c

3.8 ± 0.4d

100 ± 7b

0.95 ± 0.50b

138 ± 126

12 hours

     

  Control (n = 19)

137 ± 6

4.3 ± 0.6

104 ± 5

1.40 ± 0.58

186 ± 135

  Lactate (n = 19)

143 ± 5b,e

3.6 ± 0.4b,e

99 ± 7b

0.96 ± 0.45d

134 ± 123

24 hours

     

  Control (n = 19)

138 ± 5

4.3 ± 0.5

104 ± 4

1.30 ± 0.49

168 ± 133

  Lactate (n = 18)

146 ± 6b,e

3.3 ± 0.4b,e

98 ± 9b

0.98 ± 0.40d

136 ± 128

48 hours

     

  Control (n = 18)

138 ± 7

4.3 ± 0.4

102 ± 4

1.22 ± 0.33

156 ± 130

  Lactate (n = 18)

144 ± 6b,e

3.8 ± 0.5

103 ± 6

1.15 ± 0.41

129 ± 119

  1. aCl - = Plasma chloride concentration (mmol/L), Crea = Plasma creatinine concentration (μmol/L), K+ = Plasma potassium concentration (mmol/L), Na+ = Plasma sodium concentration (mmol/L), P = Plasma phosphate concentration (mmol/L). bP < 0.01 compared to baseline, cP < 0.05, dP < 0.05, eP < 0.01 intergroup comparison. Data are expressed as mean ± SD.