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Table 2 Evolution of haemodynamic and selected transthoracic echocardiography parameters during the study period a

From: Half-molar sodium lactate infusion improves cardiac performance in acute heart failure: a pilot randomised controlled clinical trial

Time points MAP HR SV TAPSE SmTDI E/ E
Baseline       
  Control 78 ± 15 97 ± 23 50.6 ± 13.7 16.3 ± 5 6.0 ± 0.02 17.3 ± 8.3
  Lactate 77 ± 16 95 ± 24 49 ± 19.4 14.7 ± 5.5 5.84 ± 0.02 14.4 ± 6.8
24 hours       
  Control 78 ± 12 91 ± 14 53.3 ± 13.5 16 ± 5.5 6.53 ± 0.02 13.5 ± 4.7a
  Lactate 79 ± 17 95 ± 15 59.6 ± 20b 18.3 ± 7b 7.0 ± 0.04 15.2 ± 7.6
48 hours       
  Control 77 ± 15 91 ± 15 52.3 ± 16 17.1 ± 5.7 6.5 ± 0.02 13.8 ± 5.7a
  Lactate 85 ± 18 89 ± 17 54.1 ± 26.5 18.1 ± 7.8a 6.2 ± 0.03 15.9 ± 9.7
  1. aE/E′ = Ratio of early peak diastolic transmitral Doppler flow velocity to early peak diastolic tissue Doppler velocity of the mitral annulus (averaged medial and lateral); HR = heart rate (beats/min); MAP = Mean arterial pressure (mmHg); SmTDI = Systolic motion of the mitral annulus (averaged medial and lateral) by tissue Doppler imaging (cm/s); SV = Stroke volume; TAPSE = Tricuspid annular plane systolic excursion (mm). bP < 0.05 and cP < 0.01 compared to baseline values. Data are expressed as mean ± SD.