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Table 1 Demographic, epidemiologic and clinical characteristics of 27 patients with H7N9 virus infection a

From: Immune derangement occurs in patients with H7N9 avian influenza

Variables Values
Age (years) 62 ± 14
Male, n (%) 16 (59.3)
Smoker, n (%) 8 (29.6)
Exposure to live poultry, n (%) 16 (59.3)
Underlying conditions, n (%)  
 Any 15 (55.6)
 Hypertension 13 (48.1)
 Coronary heart disease 2 (7.4)
 Diabetes mellitus 3 (11.1)
 Chronic obstructive pulmonary disease 1 (3.7)
 Other 7 (25.9)
Days between disease onset and admission 1.0 (0.5 to 19.0)
White blood cell count (109/L) 5.1 ± 3.0
Hemoglobin (g/dl) 123 ± 24
Platelet count (109/L) 132 ± 46
Alanine aminotransferase (U/L) (n = 26) 36 (12 to 262)
Creatinine (μmol/L) 57 (25 to 266)
Potassium (mmol/L) 4.37 ± 0.48
Sodium (mmol/L) 139 ± 4
International normalized ratio 1.08 ± 0.093
D-dimer (μg/L) (n = 26) 2,790 (120 to 42,920)
PaO2:FiO2 ratio 143.26 ± 58.38
Chest radiological abnormalities  
 Involvement of both lungs (n = 26) 18 (69.2)
 Ground-glass opacities (n = 21) 2 (8.7)
 Pulmonary consolidation 25 (92.6)
 APACHE II score 22.26 ± 7.70
Complications  
 Acute respiratory distress syndrome, n (%) 19 (70.4)
 Secondary infection, n (%) 13 (48.1)
 Liver damage, n (%) (n = 26) 12 (44.4)
 Shock, n (%) 6 (22.2)
 Acute renal injury, n (%) 1 (3.7)
 Antiviral therapy with oseltamivir, n (%) 27 (100)
 Glucocorticoid therapy, n (%) 10 (37.0)
 Mechanical ventilation, n (%) 13 (48.1)
 Extracorporeal membrane oxygenation, n (%) 9 (33.3)
  1. aAPACHE II, Acute Physiology and Chronic Health Evaluation II; PaO2: FiO2, ratio of partial pressure of arterial oxygen to fraction of inspired oxygen.
  2. Continuous data were expressed as mean ± SD or median (range), and categorical data were represented as number (percentage).