Table 1 Demographic, epidemiologic and clinical characteristics of 27 patients with H7N9 virus infection ^a

Age (years)

62 ± 14

Male, n (%)

16 (59.3)

Smoker, n (%)

8 (29.6)

Exposure to live poultry, n (%)

16 (59.3)

Underlying conditions, n (%)

 Any

15 (55.6)

 Hypertension

13 (48.1)

 Coronary heart disease

2 (7.4)

 Diabetes mellitus

3 (11.1)

 Chronic obstructive pulmonary disease

1 (3.7)

 Other

7 (25.9)

Days between disease onset and admission

1.0 (0.5 to 19.0)

White blood cell count (10⁹/L)

5.1 ± 3.0

Hemoglobin (g/dl)

123 ± 24

Platelet count (10⁹/L)

132 ± 46

Alanine aminotransferase (U/L) (n = 26)

36 (12 to 262)

Creatinine (μmol/L)

57 (25 to 266)

Potassium (mmol/L)

4.37 ± 0.48

Sodium (mmol/L)

139 ± 4

International normalized ratio

1.08 ± 0.093

D-dimer (μg/L) (n = 26)

2,790 (120 to 42,920)

PaO₂:FiO₂ ratio

143.26 ± 58.38

Chest radiological abnormalities

 Involvement of both lungs (n = 26)

18 (69.2)

 Ground-glass opacities (n = 21)

2 (8.7)

 Pulmonary consolidation

25 (92.6)

 APACHE II score

22.26 ± 7.70

Complications

 Acute respiratory distress syndrome, n (%)

19 (70.4)

 Secondary infection, n (%)

13 (48.1)

 Liver damage, n (%) (n = 26)

12 (44.4)

 Shock, n (%)

6 (22.2)

 Acute renal injury, n (%)

1 (3.7)

 Antiviral therapy with oseltamivir, n (%)

27 (100)

 Glucocorticoid therapy, n (%)

10 (37.0)

 Mechanical ventilation, n (%)

13 (48.1)

 Extracorporeal membrane oxygenation, n (%)

9 (33.3)