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Table 1 The Appraisal of Guidelines for Research and Evaluation (AGREE)

From: Sepsis guideline implementation: benefits, pitfalls and possible solutions

Domain 1. Scope and Purpose:

The overall aim of the guideline, the specific health questions, and the target population.

Domain 2. Stakeholder Involvement:

The extent to which the guideline was developed by the appropriate stakeholders and represents the views of its intended users.

Domain 3. Rigor of Development:

The process used to gather and synthesize the evidence, the methods to formulate the recommendations, and to update them.

Domain 4. Clarity of Presentation:

The language, structure, and format of the guideline.

Domain 5. Applicability:

The likely barriers and facilitators to implementation, strategies to improve uptake, and resource implications of applying the guideline.

Domain 6. Editorial Independence:

The formulation of recommendations not being unduly biased with competing interests.

Overall assessment:

Includes the rating of the overall quality of the guideline and whether the guideline would be recommended for use in practice.