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Table 2 Characteristics of studies included in the meta-analysis a

From: Procalcitonin for diagnosis of bacterial pneumonia in critically ill patients during 2009 H1N1 influenza pandemic: a prospective cohort study, systematic review and individual patient data meta-analysis

Study

Year

PCT available n/N (assay)

Study design

Inclusion criteria

H1N1-positive (%)b

Bacterial infection (%)b

Hospital-acquired pneumonia (%)b

Antibiotics before admission (%)b

Immune disorder (%)b

Piacentini et al. [20]

2010

22/22 (not reported)

Prospective

Adults, ICU, community-acquired pneumonia

45

50 (cultures, antigen)

0

100

5

Hammond et al. [17]

2011

17/17 (VIDAS B•R•A•H•M•S PCT)

Retrospective

Adults, ICU, respiratory tract infection

82

41 (cultures)

0

n.a.

0

Cuquemelle et al. [16]

2011

52/103 (B•R•A•H•M•S KRYPTOR PCT)

Prospective

Adults, ICU, community-acquired pneumonia, H1N1-positive

100

37 (cultures, antigen)

0

0

6

Ingram et al. [18]

2010

16/25 (VIDAS B•R•A•H•M•S PCT)

Retrospective

Adults, ICU, community-acquired pneumonia, positive for H1N1 or bacterial infection

63

38 (cultures, seroconversion)

0

94

6

Paiva et al. [19]

2012

29/29 (VIDAS B•R•A•H•M•S PCT)

Prospective

Adults, ICU, pneumonia, suspected H1N1

41

21 (cultures)

0

41

14

  1. aPCT, Procalcitonin. bReferring to patients with available procalcitonin.