28-day survivors (n = 659) | 28 day nonsurvivors (n = 352) | All patients (n = 1,011) | P value | |
---|---|---|---|---|
Male | 413 (62.7%) | 221 (62.8%) | 634 (62.7%) | 0.972 |
Age (years) | 68 (55 to 75) | 72 (64 to 79) | 69 (58 to 77) | <0.001 |
ICU admission | 0.254 | |||
Elective surgery | 74 (11.2%) | 42 (11.9%) | 116 (11.5%) | |
Emergency surgery | 255 (38.7%) | 118 (33.5%) | 373 (36.9%) | |
Trauma | 10 (1.5%) | 5 (1.4%) | 15 (1.5%) | |
Medical | 304 (46.1%) | 183 (52%) | 487 (48.2%) | |
Other | 16 (2.4%) | 4 (1.1%) | 20 (2%) | |
Patient location at onset of sepsis | 0.426 | |||
Emergency department | 93 (14.1%) | 47 (13.4%) | 140 (13.9%) | |
ICU | 366 (55.6%) | 214 (60.8%) | 580 (57.4%) | |
Operating theatre | 63 (9.6%) | 22 (6.2%) | 85 (8.4%) | |
Hospital ward | 80 (12.2%) | 41 (11.6%) | 121 (12%) | |
Prehospital | 12 (1.8%) | 4 (1.1%) | 16 (1.6%) | |
IMC | 44 (6.7%) | 24 (6.8%) | 68 (6.7%) | |
Infection | 0.22 | |||
Community acquired | 300 (45.5%) | 143 (40.6%) | 443 (43.8%) | |
ICU/IMC acquired | 170 (25.8%) | 91 (25.9%) | 261 (25.8%) | |
Hospital acquired | 189 (28.7%) | 118 (33.5%) | 307 (30.4%) | |
Source of infection (multiple responses possible) | ||||
Intra-abdominal | 228 (34.7%) | 138 (39.2%) | 366 (36.3%) | 0.167 |
Pneumonia | 221 (33.7%) | 130 (36.9%) | 351 (34.9%) | 0.311 |
Urogenital | 92 (14.0%) | 30 (8.5%) | 122 (12.1%) | 0.011 |
Upper airway | 59 (9.0%) | 24 (6.8%) | 83 (8.2%) | 0.228 |
Bones/soft tissue | 47 (7.2%) | 25 (7.1%) | 72 (7.1%) | 0.966 |
Other | 67 (11.7%) | 38 (10.7%) | 105 (10.4%) | 0.863 |
Unknown | 25 (3.8%) | 25 (7.1%) | 50 (5%) | 0.022 |
ICU length of stay (days) | 11 (4 to 26) | 7 (4 to 13) | 11 (4 to 24) | 0.003 |
Hospital length of stay (days) | 32 (19 to 52) | 18 (14.5 to 21.5) | 32 (19 to 52) | 0.011 |
SOFA score | 9 (7 to 11) | 11 (9 to 15) | 10 (8 to 12) | <0.001 |
SAPS II | 45 (34 to 56) | 54 (45 to 68) | 48 (37 to 60) | <0.001 |
Lactate maximum (mmol/l) | 2.3 (1.3 to 3.9) | 4.0 (2 to 8.1) | 2.7 (1.5 to 4.9) | <0.001 |
Procalcitonin (ng/ml) | 6.3 (1.6 to 25) | 7.0 (2.2 to 21.9) | 6.5 (1.8 to 22.8) | 0.465 |