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Table 2 Patient characteristics

From: Impact of compliance with infection management guidelines on outcome in patients with severe sepsis: a prospective observational multi-center study

 

28-day survivors (n = 659)

28 day nonsurvivors (n = 352)

All patients (n = 1,011)

P value

Male

413 (62.7%)

221 (62.8%)

634 (62.7%)

0.972

Age (years)

68 (55 to 75)

72 (64 to 79)

69 (58 to 77)

<0.001

ICU admission

   

0.254

 Elective surgery

74 (11.2%)

42 (11.9%)

116 (11.5%)

 

 Emergency surgery

255 (38.7%)

118 (33.5%)

373 (36.9%)

 

 Trauma

10 (1.5%)

5 (1.4%)

15 (1.5%)

 

 Medical

304 (46.1%)

183 (52%)

487 (48.2%)

 

 Other

16 (2.4%)

4 (1.1%)

20 (2%)

 

Patient location at onset of sepsis

0.426

 Emergency department

93 (14.1%)

47 (13.4%)

140 (13.9%)

 

 ICU

366 (55.6%)

214 (60.8%)

580 (57.4%)

 

 Operating theatre

63 (9.6%)

22 (6.2%)

85 (8.4%)

 

 Hospital ward

80 (12.2%)

41 (11.6%)

121 (12%)

 

 Prehospital

12 (1.8%)

4 (1.1%)

16 (1.6%)

 

 IMC

44 (6.7%)

24 (6.8%)

68 (6.7%)

 

Infection

   

0.22

 Community acquired

300 (45.5%)

143 (40.6%)

443 (43.8%)

 

 ICU/IMC acquired

170 (25.8%)

91 (25.9%)

261 (25.8%)

 

 Hospital acquired

189 (28.7%)

118 (33.5%)

307 (30.4%)

 

Source of infection (multiple responses possible)

 Intra-abdominal

228 (34.7%)

138 (39.2%)

366 (36.3%)

0.167

 Pneumonia

221 (33.7%)

130 (36.9%)

351 (34.9%)

0.311

 Urogenital

92 (14.0%)

30 (8.5%)

122 (12.1%)

0.011

 Upper airway

59 (9.0%)

24 (6.8%)

83 (8.2%)

0.228

 Bones/soft tissue

47 (7.2%)

25 (7.1%)

72 (7.1%)

0.966

 Other

67 (11.7%)

38 (10.7%)

105 (10.4%)

0.863

 Unknown

25 (3.8%)

25 (7.1%)

50 (5%)

0.022

ICU length of stay (days)

11 (4 to 26)

7 (4 to 13)

11 (4 to 24)

0.003

Hospital length of stay (days)

32 (19 to 52)

18 (14.5 to 21.5)

32 (19 to 52)

0.011

SOFA score

9 (7 to 11)

11 (9 to 15)

10 (8 to 12)

<0.001

SAPS II

45 (34 to 56)

54 (45 to 68)

48 (37 to 60)

<0.001

Lactate maximum (mmol/l)

2.3 (1.3 to 3.9)

4.0 (2 to 8.1)

2.7 (1.5 to 4.9)

<0.001

Procalcitonin (ng/ml)

6.3 (1.6 to 25)

7.0 (2.2 to 21.9)

6.5 (1.8 to 22.8)

0.465

  1. Categorical data are expressed as absolute or relative frequencies (number (percentage); continuous data are expressed as median (interquartile range). SOFA score, lactate, and procalcitonin refer to the day of sepsis onset. P value refers to differences between survivors and nonsurvivors. IMC, intermediate care unit; SAPS, Simplified Acute Physiology Score; SOFA, Sequential Organ Failure Assessment.