Table 6 Levels of soluble vascular cell adhesion molecule-1 in neonates, children and adults
Study (reference) | Mean age | Sepsis criteria | Healthy (μg/ml)a | Number of patients (healthy) | Sepsis (μg/ml)a | Number of patients (sepsis) |
|---|---|---|---|---|---|---|
Neonates | Â | Â | Â | Â | Â | Â |
Figueras-Aloy and colleagues [49] | 0 to 14 days | SNAP-II | 928 (856 to 1,005) | 12 | 1,112 (1,072 to 1,153) | 15 |
Austgulen and colleagues [45] | 0 to 7 days | Clinical | 1,940 (1,100 to 3,500) | 168 | 1,950 (1,190 to 3,495) | 24 |
Children | Â | Â | Â | Â | Â | Â |
Andrys and colleagues [60] | 6 to 15 years | Â | 590.8 (359.6 to 822.0) | 68 | Â | Â |
Paize and colleagues [61] | 2.16 | PRISM | 600 (390 to 790) | 40 | 1,550 (1,360 to 1,910) | 20 |
Krueger and colleagues [62] | 3.5 (0.2 to 16) | ACCP/SCCM | 766 (644 to 915) | 22 | 1,239 (928 to 1,615) | 22 |
Whalen and colleagues [63] | 1 day to 17 years | Criteria of Doughty and colleaguesb | 231 ± 46 | 14 | 600 | 77 |
Nash and colleagues [64] | 9 years | Â | 790 (580 to 1,060) | 81 | Â | Â |
| Â | 15 years | Â | 780 (420 to 1,000) | Â | Â | Â |
Adults | Â | Â | Â | Â | Â | Â |
Presterl and colleagues [65] | 51 | APACHE II | 545 (374 to 829) | 20 | 2633 | 20 |
Knapp and colleagues [68] | 51 to 55 (21 to 96) | APACHE III | 569 ± 98 | 15 | 1,395 ± 801 | 28 |
Soderquist and colleagues [70] | 71 (10 to 91) | Unknown | 533 (354 to 1,018) | 15 | 1,173 (525 to 3,500) | 41 |
Hofer and colleagues [78] | 65.9 (12.4) | APACHE II | 1,524.7 (991.2 to 2,038) | 108 | 1,147.9 (883.5 to 2,074.4) | 18 |
De Pablo and colleagues [73] | 61.2 (3.2) | APACHE II | 890 | 48 | 1,600 | 52 |
Shapiro and colleagues [6] | 57 (19) | APACHE III | 1,050 | 49 | 1,550 | 95 |
Andrys and colleagues [60] | 46 | Â | 743 (338 to 1,148) | 68 | Â | Â |
Leone and colleagues [76] | 45 to 47 (16 to 21) | SIRS | 458 ± 123 | 26 | 1,604 ± 940 | 11 |