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Table 3 Levels of soluble L-selectin in neonates, children and adults

From: Soluble adhesion molecules as markers for sepsis and the potential pathophysiological discrepancy in neonates, children and adults

Study (reference) Mean age Sepsis criteria Healthy (μg/ml)a Number of patients (healthy) Sepsis (μg/ml)a Number of patients (sepsis)
Neonates       
Figueras-Aloy and colleagues [49] 0 to 14 days SNAP-II 580 (523 to 717) 12 681 (541 to 757) 15
Kourtis and colleagues [50] 0 to 2 days Clinical 1,155 75 1,331 (1,123 to 1,427) 14
Giannaki and colleagues [47] At term   674 ± 223 40   
Rebuck and colleagues [43] At term   463 (338 to 557) 22   
Koenig and colleagues [42] 0 to 7 days   324 ± 24 10   
Children       
Kourtis and colleagues [59] Children   3,356 (2,818 to 3,894) 100   
Briassoulis and colleagues [19] 6.5 (2.8) PRISM 3,750 ± 321 10 6,263 ± 3,813 10
Adults       
Weigand and colleagues [66] 58.7 (4.4) ACCP/SCCM 460 7 400 14
Kourtis and colleagues [50] Adult   950 (700 to 1,220) 75   
Schleiffenbaum and colleagues [23] Adult   1,600 ± 800 63   
Giannaki and colleagues [47] Adult   938 ± 181 40   
Rebuck and colleagues [43] Adult   717 (410 to 822) 22   
Koenig and colleagues [42] Adult   537 ± 28 9   
  1. ACCP/SCCM, American college of chest physicians/society of critical care medicine; PRISM, pediatric risk of mortality; SNAP, score for neonatal acute physiology. aData presented as mean (range) or mean ± standard deviation. Ages expressed in years unless otherwise stated.