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Table 2 Hematologic, hemodynamic, and gas exchange variables and Sequential Organ Failure Assessment score (baseline and 1 hour after blood transfusion)

From: Microcirculatory effects of the transfusion of leukodepleted or non-leukodepleted red blood cells in patients with sepsis: a pilot study

 

Non-leukodepleted group

 

Leukodepleted group

 
 

n = 10

 

n = 10

 
 

Before

After

P a

Before

After

P a

Hb, g/dL

8.4 (7.9–8.8)

10.4 (9.9–11.5)

<0.01

8.3 (7.4–8.6)

10.4 (9.9–10.8)

<0.01

Hct, %

26.7 (26.0–28.0)

32.5 (29.9–34.6)

<0.01

25.9 (22.9–27.9)

31.5 (29.5–33.5)

<0.01

HR, bpm

72 (59–98)

70 (60–86)

0.20

91 (79–97)

88 (81–94)

0.60

MAP, mm Hg

70 (67–77)

77 (72–98)

0.04

85 (75–106)b

89 (78–96)

0.68

Urine output, mL/d

3,145 (2,516–3,625)

3,572 (2,385–4,266)

0.99

3,520 (2,756–4,854)

4,636 (2,967–5,314)

0.07

T, °C

36.8 (35.9–37.3)

36.7 (36.1–37.4)

0.48

36.9 (36.5–37.4)

37.4 (36.5–37.9)

0.12

WBCs, ×103/μL

11.9 (5.2–17.3)

12.5 (5.1–17.2)

0.99

8.7 (5.9–15.4)

8.6 (6.6–13.3)

0.76

PLTs, ×103/μL

190 (112–225)

198 (87–216)

0.86

163 (90–336)

172 (100–332)

0.27

pH

7.48 (7.36–7.54)

7.49 (7.37–7.52)

0.07

7.48 (7.46–7.5)

7.48 (7.47–7.50)

0.99

PaO2, mm Hg

123 (103–149)

105 (96–125)

0.06

133 (94–183)

137 (119–153)

0.41

PaCO2, mm Hg

42 (36–45)

42 (37–46)

0.94

39 (34–41)

39 (35–41)

0.76

PaO2/FiO2

230 (206–309)

215 (173–298)

0.36

323 (243–408)b

287 (270–374)

0.34

BE, mEq/L

5.7 (1.8–10.5)

5.3 (1.3–9.5)

0.03

3.7 (2.8–5.9)

3.9 (2.2–5.8)

0.73

Lac, mmol/L

1.2 (0.9–1.7)

1.3 (1.0–1.8)

0.44

1 (0.7–1.4)

1.1 (0.7–1.4)

0.53

SOFA score

8 (5–12)

8 (3.4–12)

0.85

5 (3–7)

5 (3–8)

0.59

  1. aPre versus post, Wilcoxon matched–pairs signed–rank test. bP <0.05, versus non–leukodepleted red blood cell group at the same time point, Mann–Whitney U test. BE, base excess; FiO2, fraction of inspired oxygen; Hb, hemoglobin; Hct, hematocrit; HR, heart rate; Lac, arterial lactate levels; MAP, mean arterial pressure; PaCO2, arterial partial pressure of carbon dioxide; PaO2, arterial partial pressure of oxygen; PLT, platelet; SOFA, Sequential Organ Failure Assessment; T, body temperature; WBC, white blood cell.