Figure 1From: Hypercapnia attenuates ventilator-induced diaphragm atrophy and modulates dysfunctionCourse of blood pH, CO 2, O 2 and MAP during 18Â hours of mechanical ventilation. (a) As expected increasing Fico2 reduces blood pH. *Two-way repeated measure analysis showed that pH values over time were significantly different between groups. (b) CO2 was significantly increased at the end of experiment in hypercapnic rats. *Two-way repeated measure analysis showed that CO2 values over time were significantly different between groups. (c) O2 was not significantly different between mechanically ventilated groups. (d) MAP was significantly lower at 4Â hours and at the end of experiment in hypercapnic rats. *Two-way repeated measure analysis showed that MAP was significantly different between groups at 4, 12, 16 and 18Â hours of mechanical ventilation. MAP, mean arterial pressure.Back to article page