From: Prothrombin complex concentrates and a specific antidote to dabigatran are effective ex-vivo in reversing the effects of dabigatran in an anticoagulation/liver trauma experimental model
Baseline
Low dabigatran
High dabigatran
Post-trauma
Haemoglobin (g/L)
10.5 ± 0.7
10.2 ± 0.8
9.5 ± 0.4
4.5 ± 0.7
Platelets (× 103/μL)
388 ± 51
403 ± 36
355 ± 66
202 ± 50
Fibrinogen (mg/dL)
161 ± 16
135 ± 13
118 ± 19
64 ± 12