Figure 4From: Prothrombin complex concentrates and a specific antidote to dabigatran are effective ex-vivo in reversing the effects of dabigatran in an anticoagulation/liver trauma experimental modelThromboelastometry parameters after intravenous administration of dabigatran. After 90 minutes of intravenous infusion of dabigatran, the EXTEM assay was performed using a ROTEM device. Data are shown as mean ± SD. *P <0.05 versus control. PCC, prothrombin complex concentrate; aPCC, activated PCC; rFVIIa, recombinant activated factor VII; aDabi-Fab, antibody fragment to dabigatran.Back to article page