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Figure 1 | Critical Care

Figure 1

From: Prothrombin complex concentrates and a specific antidote to dabigatran are effective ex-vivo in reversing the effects of dabigatran in an anticoagulation/liver trauma experimental model

Figure 1

Prothrombin time at the low dabigatran (A), high dabigatran (B) and post-trauma (C) time points. Prothrombin time was obtained on a coagulometer using Innovin to determine the effect of ex vivo haemostatic therapy at various time points. Grey dotted lines indicate mean baseline values. *P <0.05 versus control. PCC, prothrombin complex concentrate; aPCC, activated PCC; rFVIIa, recombinant activated factor VII; aDabi-Fab, antibody fragment to dabigatran.

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Critical Care

ISSN: 1364-8535