Table 1 Baseline characteristics of total ECMO study population ( n = 191) and for tertiles of butyrylcholinesterase
Total study population (n = 191) | 1sttertile | 2ndtertile | 3rdtertile | P value* | |
|---|---|---|---|---|---|
Tertiles of cholinesterase, kU/l (IQR) | 5.04 (3.38-6.31) | 2.81 (2.35-3.39) | 5.04 (4.60-5.04) | 7.45 (6.57-8.40) | ------ |
Age, median years (IQR) | 62 (51–69) | 65 (52–70) | 61 (50–70) | 62 (52–69) | 0.697 |
Male sex n (%) | 136 (71%) | 48 (75%) | 44 (68%) | 44 (71%) | 0.613 |
SAPS II at ICU admission, n (%) | 44 (31–60) | 47 (37–57) | 47 (33–58) | 47 (31–61) | 0.790 |
EuroSCORE (additive), points (IQR) | 10 (6–13) | 12 (8–13) | 10 (6–14) | 8 (5–11) | 0.017 |
Procedure duration, hour (IQR) | 7.2 (4.8-9.0) | 7.0 (4.7- 8.5) | 7.1 (5.3-9.0) | 7.8 (4.8-9.5) | 0.265 |
ECMO duration, median days (IQR) | 4 (2–6) | 6 (3–7) | 5 (2–7) | 4 (2–7) | 0.279 |
Time on mechanical ventilation, median days (IQR) | 11 (4–19) | 9 (3–16) | 13 (6–24) | 10 (4–19) | 0.427 |
IABP, n (%) | 29 (15%) | 9 (14%) | 11 (17%) | 9 (15%) | 0.940 |
Hypertension, n (%) | 86 (45%) | 24 (38%) | 24 (37%) | 38 (61%) | 0.008 |
Diabetes, n (%) | 42 (22%) | 12 (19%) | 17 (26%) | 13 (21%) | 0.757 |
Hypercholesterolemia, n (%) | 54 (28%) | 11 (17%) | 22 (34%) | 21 (34%) | 0.037 |
Coronary artery disease, n (%) | 75 (42%) | 25 (41%) | 26 (43%) | 24 (41%) | 0.963 |
Left ventricular ejection fraction | |||||
30% to 44%, n (%) | 32 (17%) | 13 (20%) | 10 (15%) | 9 (15%) | 0.383 |
<30%, n (%) | 81 (42%) | 28 (44%) | 31 (48%) | 22 (36%) | 0.354 |
Creatinine, mg/dl (IQR) | 1.36 (1.10–1.88) | 1.56 (1.17-2.23) | 1.47 (1.11-1.94) | 1.25 (1.03-1.69) | 0.245 |
Estimated GFR, ml/min/1.73 m2 (IQR) | 57 (38–77) | 53 (35–74) | 58 (37–67) | 64 (45–88) | 0.045 |
Albumin, g/L (IQR) | 36 (28–42) | 28 (23–35) | 37 (31–41) | 42 (38–45) | <0.001 |
ASAT, U/L (IQR) | 39 (26–111) | 48 (32–138) | 48 (28–123) | 31 (24–48) | 0.345 |
ALAT, U/L (IQR) | 32 (18—61) | 34 (15–81) | 36 (20–58) | 29 (18–49) | 0.486 |
Gamma-GT, U/L (IQR) | 59 (33—121) | 76 (28–151) | 75 (39–149) | 47 (31–88) | 0.089 |