Skip to main content

Table 4 Prognostic factors of patients with acute ischemic stroke

From: Statin therapy reduces oxidized low density lipoprotein level, a risk factor for stroke outcome

 

Good outcome (n = 81)

Poor outcome (n = 39)

Crude odds ratio (95% CI)

P- value†

Adjusted odds ratio (95% CI)

P- value

Age, y

59.0 ± 10.6

62.6 ± 10.4

1.04 (1.00, 1.08)

0.08

-

-

Sex, male, %

76.5

69.2

0.69 (0.32, 1.48)

0.39

-

-

Hypertension, %

69.1

79.5

1.85 (0.77, 4.43)

0.23

-

-

Diabetes mellitus, %

35.8

33.3

0.86 (0.42, 1.78)

0.79

-

-

Hyperlipidemia, %

48.1

46.2

0.95 (0.47, 1.91)

0.84

-

-

Coronary artery disease, %

2.5

15.4

4.65 (1.29, 16.8)

0.01

-

-

Intracranial atherosclerosis, %

36.3

35.1

1.17 (0.56, 2.45)

0.91

-

-

Patients with Statin therapy, %

54.3

33.3

0.58 (0.29, 1.18)

0.05

-

-

Median NIHSS (IQR) scores on admission

3 (2.0 to 4.5)

8.0 (7.0 to 12.75)

1.43 (1.25, 1.64)

<0.0001

1.55 (1.20, 1.99)

0.001

Laboratory data on admission

      

  White blood cells, × 103/mL

7.0 ± 2.2

7.6 ± 1.9

0.98 (0.83, 1.16)

0.81

-

-

  Red blood cells, × 106/mL

4.9 ± 0.8

4.6 ± 0.6

0.70 (0.41, 1.20)

0.12

-

-

  Platelet counts, × 104/mL

22.6 ± 6.2

18.5 ± 5.3

0.99 (0.98, 0.99)

0.001

-

-

  Total cholesterol, mg/dL

188.3 ± 35.7

200.6 ± 43.9

1.01 (1.00, 1.02)

0.11

-

-

  LDL-cholesterol, mg/dL

114.4 ± 34.2

129.2 ± 38.8

1.01 (1.00, 1.02)

0.04

-

-

  HDL-cholesterol, mg/dL

43.8 ± 10.6

46.4 ± 12.9

1.02 (0.99, 1.05)

0.24

-

-

  Triglyceride, mg/dL

148.6 ± 79.1

127.2 ± 73.6

0.99 (0.99, 1.01)

0.16

-

-

  HbA1c, %

7.0 ± 2.2

6.8 ± 1.9

0.97 (0.82, 1.16)

0.68

-

-

  hs-CRP

3.2 ± 0.4

5.34 ± 0.9

1.15 (1.03, 1.30)

0.02

-

-

Systolic BP, mmHg

144.7 ± 24.2

145.1 ± 28.9

1.00 (0.99, 1.02)

0.94

-

-

Diastolic BP, mmHg

83.6 ± 13.6

84.5 ± 14.2

1.01 (0.98, 1.04)

0.75

-

-

Infarct volume, cm3

2.5 ± 0.7

4.2 ± 1.1

1.00 (0.99, 1.01)

0.12

-

-

Ox-LDL on admission, U/L†

31.4 ± 2.7

37.7 ± 3.2

1.06 (1.03, 1.10)

0.005

1.09 (1.02, 1.18)

0.009

Ox-LDL on day 7, U/L

28.0 ± 2.7

35.2 ± 23.4

1.07 (1.03, 1.11)

0.008

-

-

Ox-LDL on day 30, U/L

25.6 ± 2.9

32.4 ± 3.2

1.09 (1.03, 1.14)

0.009

-

-

  1. Good outcome: three-month modified Rankin scale (mRS) (0 to 2); poor outcome: three-month mRS (3 to 6).
  2. LDL, low density lipoprotein; HDL, high density lipoprotein; BP, blood pressure; HbA1c, hemoglobin A1c; hs-CRP, high-sensitivity C-reactive protein; NIHSS, National Institutes of Health Stroke Scale; Ox-LDL, oxidized low density lipoprotein. †The odds ratio was calculated by univariate logistic regression.
Back to article page

Critical Care

ISSN: 1364-8535