Microorganisms isolated in each bacteraemia group. Left panel, 2000; right panel, 2013. Top panel, community-acquired bacteraemia; Middle panel, hospital-acquired bacteraemia; lower panel, ICU-acquired bacteraemia. Shaded areas represent numbers of methicillin-resistant strains for S. aureus and coagulase-negative staphylococci; vancomycin-resistant strains for Enterococcus spp.; multidrug-resistant strains for Gram-negative pathogens; and fluconazole-resistant strains for Candida spp.